Alzheimer’s Disease – Page 3

First evidence of human-to-human transmission of Alzheimer’s disease

Posted on January 30, 2024 by Rich Haridy

Some patients treated with a type of human growth hormone collected from deceased individuals were found to develop signs of Alzheimer's disease at unusually young ages

A team of researchers at University College London has reported the first-ever clear evidence of human-to-human transmission of Alzheimer’s disease. Across a handful of extraordinarily rare case studies the researchers demonstrated how a human growth hormone treatment transplanted toxic proteins into children and caused the development of early-onset Alzheimer’s.

Category: Science

Tags: Alzheimer’s Disease, Brain, University College London, Neurological, Dementia

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Little changes science recommended in 2023 for big health benefits

Posted on January 1, 2024 by Michael Franco

You really can see big health benefits from incremental changes, says a substantial amount of research from 2023

While 2023 saw some major breakthroughs in the fields of medicine and biology (daily cancer pill anyone?), it was also a year in which researchers homed in on a variety of relatively small and simple lifestyle modifications that can positively impact human health. These are discoveries you can use right now to potentially boost your health, fight disease, and live longer. As the year draws to a close, we thought we’d share some of them with you so that you can put a little science power behind whatever winds up on your resolution list this year.

Category: Health & Wellbeing, Lifestyle

Tags: Health, Diet, Exercise, Weight Loss, Sleep, Diabetes, Alzheimer’s Disease, Food, Coffee, Nutrition, best-of-2023

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“Chemical chaperone” improves Alzheimer’s signs in early & late disease

Posted on December 21, 2023 by Paul McClure

Treatment with a supplementary 'chemical chaperone' has been shown to reduce protein plaques and improve cognitive performance in Alzheimer's disease

A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The findings could lead to novel treatments to help treat this debilitating disease.

Category: Medical, Science

Tags: Alzheimer’s Disease, Protein, Brain, University of Pennsylvania

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Rogue protein linked to early-onset dementia identified

Posted on December 8, 2023 by Bronwyn Thompson

A visualization of the structure of TAF15 amyloid filaments (in yellow), as detected by cryo-EM in the brains of four dementia patients

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.

Category: Medical, Science

Tags: Medical Research Council, Dementia, Alzheimer’s Disease, Protein, Brain, Neuroscience, Neurological

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Twice-daily brain zaps may boost ‘rewiring’ & functioning in Alzheimer’s

Posted on December 6, 2023 by Paul McClure

A study found that twice-daily non-invasive electrical stimulation improved brain functioning in patients with Alzheimer's disease

Research has found that non-invasively applying a mild electrical current to the brain twice a day for six weeks improved cognitive functioning and plasticity, the ability of the brain to ‘rewire’ itself, in patients with Alzheimer’s disease. The treatment may be an effective way of reducing – or even reversing – the effects of the condition.

Category: Medical, Science

Tags: Alzheimer’s Disease, Electricity, Brain, Neurological, Dementia

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Certain personality traits could help protect against dementia

Posted on December 1, 2023 by Paul McClure

Possessing certain personality traits increases the risk of a dementia diagnosis, while others lessen it, research has found

New research has found that some personality traits increase the risk of a dementia diagnosis, whereas others reduce it. Interestingly, no consistent association was seen between personality and dementia-related brain pathology. The findings suggest that targeting personality traits in interventions earlier in life may be a way of reducing dementia risk in the long term.

Category: Health & Wellbeing, Lifestyle

Tags: Dementia, Alzheimer’s Disease, Personality, UC Davis

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Brain cell gene changes linked to neuroinflammation seen in Alzheimer’s

Posted on November 30, 2023 by Paul McClure

A study has linked genetic changes in the brain's immune cells to the neuroinflammation seen in Alzheimer's disease

New research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.

Category: Medical, Science

Tags: Alzheimer’s Disease, Brain, Inflammatory, Genetics, Brigham and Women’s Hospital

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