Big study uncovers 22 links between viral infections and brain disease

A new study cannot determine a causal relationship between viral infections and neurodegenerative disease, but there is a correlation

New research looking at health records from nearly half a million people has identified 22 different associations between viral infections and neurodegenerative diseases. Influenza, encephalitis and other viral infections all were linked to increased rates of brain diseases such as Parkinson’s, Alzheimer’s and MS.

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Hormone replacement therapy may reduce dementia risk in women

HRT was associated with larger entorhinal and amygdala volumes and better responses to memory tests

New research has found hormone replacement therapy (HRT) can be linked with better brain health and cognition among women with a high genetic risk of developing Alzheimer’s disease. The findings are observational, and cannot determine causality, but they do build on a body of study trying to understand why women are generally more likely to develop Alzheimer’s compared to men.

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More evidence of role gut bacteria may play in Alzheimer’s decline

Research has found animals with no gut bacteria showed lower rates of neurodegeneration than animals with normal microbiomes

A fascinating new study has shed more light on how the trillions of microbes in our gut could be affecting our brain health. The animal research found mice engineered to develop Alzheimer’s developed significantly fewer signs of neurodegeneration when raised with no gut bacteria, suggesting the microbiome may play a crucial role in the development of neurodegenerative disease.

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Implantable lens could warn of Alzheimer’s disease

The lens could be implanted behind the cornea of people known to be at risk of Alzheimer's

As is the case with so many other things, the sooner that Alzheimer’s disease is detected, the more that can be done to slow its progress. An experimental implantable lens could help, by changing in appearance at the early stages of the illness.

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Another controversial FDA approval for a new Alzheimer’s medication

The approval of a drug for Alzheimer's follows several recently reported deaths of clinical trial participants

The U.S. Food and Drug Administration (FDA) has approved a new drug for patients in the early-stages of Alzheimer’s disease. Called Leqembi (lecanemab) the treatment was heralded last year as a major breakthrough in Alzheimer’s therapy following early Phase 3 data indicating it could slow the progression of cognitive decline. But growing concerns over the drug’s safety and real-world efficacy have led to acrimonious division amongst researchers, with some suggesting the drug should not be authorized for wide use.

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Signs of Alzheimer’s found in brains of beached dolphins

New research bolsters a hypothesis dubbed

Could the phenomenon of whale and dolphin strandings be due to Alzheimer’s-like cognitive deficits in pod leaders that draw groups into shallow waters? A new study looking at brain tissue from stranded dolphins reveals pathological signs that resemble what is seen in human patients with Alzheimer’s disease.

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New evidence links nasal viral infections to rapid Alzheimer’s progression

A new study has found evidence that viral infections in the olfactory system could trigger a cascade of events that can lead to Alzheimer's disease

A new study has presented more evidence backing up a hypothesis suggesting viral infections in the olfactory system can accelerate the progression of Alzheimer’s disease (AD). Instead of focusing on specific viruses, the research looked at the relationship between biomarkers of viral infections and neurodegeneration in the hippocampus.

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First human trials test light & sound therapy for Alzheimer’s disease

A promising new therapy for Alzheimer's involves exposure to a 40-Hz flickering light and sound tone for an hour a day

A new study published in the journal PLoS ONE has reported on the first human tests of an experimental therapy using sound and light to treat Alzheimer’s disease (AD). The initial findings are promising, with the unique treatment leading to some neurological and cognitive improvements, but the small trial size means more study is needed before anyone can say this type of therapy works.

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Risk of Alzheimer’s linked with genetic propensity for ADHD

A new study has found people with a high genetic risk score for ADHD display faster rates of cognitive decline compared to a matched group without the same genetic propensity

A genetic predisposition to attention-deficit/hyperactivity disorder (ADHD) has been linked to an increased risk of cognitive decline and Alzheimer’s disease in old age, according to new research from the University of Pittsburgh. The findings are the first to associate ADHD genetic risk with age-related cognitive impairment.

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Hearing aids slow cognitive decline, but reasons why still a mystery

A new meta-study has found using a hearing aid can be linked to lower risk of cognitive decline but it's still unclear exactly how the devices are preventing dementia

A first-of-its-kind meta-analysis comprising more than 100,000 participants has found a significant association between the use of hearing aids and a reduced risk of dementia. The findings raise the curious suggestion that using hearing restoration devices could somehow slow the progression of cognitive decline.

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