GLP-1 weight-loss drugs may pivot to treat Alzheimer’s and Parkinson’s

Scientists are still discovering the potential medical 'superpowers' of GLP-1 receptor agonist drugs

In yet another surprise attribute of the new class of obesity drugs, scientists have found that GLP-1 receptor agonists can also subdue brain inflammation, giving them a potential ‘superpower’ in the fight against Alzheimer’s and Parkinson’s diseases.

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First evidence of human-to-human transmission of Alzheimer’s disease

Some patients treated with a type of human growth hormone collected from deceased individuals were found to develop signs of Alzheimer's disease at unusually young ages

A team of researchers at University College London has reported the first-ever clear evidence of human-to-human transmission of Alzheimer’s disease. Across a handful of extraordinarily rare case studies the researchers demonstrated how a human growth hormone treatment transplanted toxic proteins into children and caused the development of early-onset Alzheimer’s.

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MRI ‘signature’ may reveal dementia 5-to-10 years before symptoms appear

Comparing the brain MRIs of people with and without dementia, researchers have identified an accurate ‘signature’ that may signal a person’s risk of developing the disease five to 10 years before symptoms appear. The novel biomarker could provide an ea… Continue reading MRI ‘signature’ may reveal dementia 5-to-10 years before symptoms appear

ID of five subtypes of Alzheimer’s has huge implications for treatment

This breakthrough study could be pivotal in the research into and treatment of Alzheimer's disease

An international team of neuroscientists has for the first time identified five distinct subtypes of Alzheimer’s disease, in what could be a breakthrough for treatment approaches and efficacy. They call for researchers and medical professionals to look at the disease not as a single diagnosis but five specific types of Alzheimer’s.

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Pets may slow age-related cognitive decline in those living alone

A study has found an association between pet ownership by older adults living alone and slower cognitive decline

A new study has found that, for older adults living alone, owning a pet was linked to slower rates of decline in some aspects of cognition and may completely offset the association between living alone, a recognized dementia risk, and cognitive decline.

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Rogue protein linked to early-onset dementia identified

A visualization of the structure of TAF15 amyloid filaments (in yellow), as detected by cryo-EM in the brains of four dementia patients

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.

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Twice-daily brain zaps may boost ‘rewiring’ & functioning in Alzheimer’s

A study found that twice-daily non-invasive electrical stimulation improved brain functioning in patients with Alzheimer's disease

Research has found that non-invasively applying a mild electrical current to the brain twice a day for six weeks improved cognitive functioning and plasticity, the ability of the brain to ‘rewire’ itself, in patients with Alzheimer’s disease. The treatment may be an effective way of reducing – or even reversing – the effects of the condition.

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Certain personality traits could help protect against dementia

Possessing certain personality traits increases the risk of a dementia diagnosis, while others lessen it, research has found

New research has found that some personality traits increase the risk of a dementia diagnosis, whereas others reduce it. Interestingly, no consistent association was seen between personality and dementia-related brain pathology. The findings suggest that targeting personality traits in interventions earlier in life may be a way of reducing dementia risk in the long term.

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Too much ‘good’ cholesterol could be bad for dementia, says study

It’s generally considered a good thing to have elevated levels of HDL cholesterol, also commonly referred to as “good” cholesterol. But new research indicates that when those HDL levels climb too high, dementia could be an unwanted side effect.Continue… Continue reading Too much ‘good’ cholesterol could be bad for dementia, says study