Beyond plaques: New Alzheimer’s treatment pathway discovered

New pathways to combating and treating Alzheimer's disease are emerging as researchers look for mechanisms beyond brain plaques

Researchers have discovered that limiting a certain enzyme can have a dramatic impact in protecting against the effects of Alzheimer’s disease. The finding could lead to a new class of drugs that fight the disease.

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Microbes stomp daffodils in creating valuable anti-Alzheimer’s drug

A microbial fermentation process proved better than daffodil extract at creating an important anti-dementia drug

Using an AI-based approach, researchers found a better way to create the drug galantamine, commonly prescribed to people suffering from Alzheimer’s and other forms of dementia. The fermentation-based technique could boost the drug’s availability.

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Magnetite pollution is damaging our brains and causing Alzheimer’s

A little-known and hard-to-filter pollutant has been linked to elevated Alzheimer's risk. The only solution may be decarbonization

Air pollution in urban environments has long been associated with poor health. Breast cancer, immune dysfunction, osteoporosis, heart problems and dementia have all been linked to air pollution, however, understanding exactly how poor air quality is explicitly causing disease has been a challenge for researchers.

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COVID brain fog drains 3-6 IQ points for more than a year

Even mild cases of COVID cause significant, measurable cognitive deficits compared to those never infected with the virus, according to one of the largest studies of its type. COVID brain fog is real, and it can sap up to six IQ points for at least a y… Continue reading COVID brain fog drains 3-6 IQ points for more than a year

GLP-1 weight-loss drugs may pivot to treat Alzheimer’s and Parkinson’s

Scientists are still discovering the potential medical 'superpowers' of GLP-1 receptor agonist drugs

In yet another surprise attribute of the new class of obesity drugs, scientists have found that GLP-1 receptor agonists can also subdue brain inflammation, giving them a potential ‘superpower’ in the fight against Alzheimer’s and Parkinson’s diseases.

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First evidence of human-to-human transmission of Alzheimer’s disease

Some patients treated with a type of human growth hormone collected from deceased individuals were found to develop signs of Alzheimer's disease at unusually young ages

A team of researchers at University College London has reported the first-ever clear evidence of human-to-human transmission of Alzheimer’s disease. Across a handful of extraordinarily rare case studies the researchers demonstrated how a human growth hormone treatment transplanted toxic proteins into children and caused the development of early-onset Alzheimer’s.

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MRI ‘signature’ may reveal dementia 5-to-10 years before symptoms appear

Comparing the brain MRIs of people with and without dementia, researchers have identified an accurate ‘signature’ that may signal a person’s risk of developing the disease five to 10 years before symptoms appear. The novel biomarker could provide an ea… Continue reading MRI ‘signature’ may reveal dementia 5-to-10 years before symptoms appear

ID of five subtypes of Alzheimer’s has huge implications for treatment

This breakthrough study could be pivotal in the research into and treatment of Alzheimer's disease

An international team of neuroscientists has for the first time identified five distinct subtypes of Alzheimer’s disease, in what could be a breakthrough for treatment approaches and efficacy. They call for researchers and medical professionals to look at the disease not as a single diagnosis but five specific types of Alzheimer’s.

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Pets may slow age-related cognitive decline in those living alone

A study has found an association between pet ownership by older adults living alone and slower cognitive decline

A new study has found that, for older adults living alone, owning a pet was linked to slower rates of decline in some aspects of cognition and may completely offset the association between living alone, a recognized dementia risk, and cognitive decline.

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