Inflammation or infection: The debate over COVID’s effect on the brain

Perhaps one of the most persistent debates around COVID has been the reason behind the disease’s neurological symptoms. Ever since SARS-CoV-2 emerged in late 2019 the virus has been known for its novel effects on the brain: Extreme fatigue, cognitive a… Continue reading Inflammation or infection: The debate over COVID’s effect on the brain

Never-before-seen immune cell a “game-changer” for food allergy sufferers

Researchers have discovered a never-before-identified type of memory B cell, an immune cell that ‘remembers’ what a person is allergic to, potentially opening the door to new therapeutics to treat allergies, including life-threatening food allergies.Co… Continue reading Never-before-seen immune cell a “game-changer” for food allergy sufferers

Getting vaccines in different arms improves effectiveness, study finds

Researchers have found that getting a vaccine booster shot in a different arm from the one you got the first in may improve the body’s immune response up to four-fold. While they exclusively studied responses to the COVID-19 vaccine, they suspect this … Continue reading Getting vaccines in different arms improves effectiveness, study finds

“Zombie” COVID particles may be responsible for lethal disease

Following the emergence of SARS-CoV-2 in 2020 there are now seven different coronaviruses known to infect humans. Four of those are associated with generally harmless common respiratory infections, but the other three (SARS, SARS-CoV-2 and MERS) are mu… Continue reading “Zombie” COVID particles may be responsible for lethal disease

New molecule triggers burst of white blood cells to fight infections

White blood cells are important foot soldiers in the immune system, but their numbers can be cut by health conditions or treatments like chemotherapy. Yale scientists have now discovered a molecule that can be given to quickly boost their numbers back … Continue reading New molecule triggers burst of white blood cells to fight infections

Blood protein ‘signature’ may be key to long COVID diagnosis & treatment

Undertaking a study of proteins found in the complement system, an important part of the immune system, of patients with long COVID, researchers have identified a blood protein ‘signature’ that may improve the diagnosis and lead to a treatment for the … Continue reading Blood protein ‘signature’ may be key to long COVID diagnosis & treatment

“Armored” immune cells make their own medicine to keep fighting cancer

A new form of immunotherapy helps immune cells “armor” themselves against exhaustion by releasing their own medicine to keep them going in the fight against cancer. In a small ongoing trial, 100% of patients have achieved complete remission, and the ne… Continue reading “Armored” immune cells make their own medicine to keep fighting cancer

Cannibalistic cells could provide an edge in future cancer treatments

Following a trail of evidence that started with a study of fruit flies nearly 25 years ago, researchers have found adding a hyperactive form of the protein Rac2 to macrophages, immune cells that eat pathogens, causes them to cannibalize T cells. The no… Continue reading Cannibalistic cells could provide an edge in future cancer treatments

Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%

By fitting microparticle ‘backpacks’ to important inflammatory cells called macrophages, researchers significantly reduced lesion size and inflammation caused by traumatic brain injury. Working with biology rather than against it, this novel approach h… Continue reading Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%

Plant non-steroidal anti-inflammatory leaves immune system intact

Researchers have developed a novel non-steroidal anti-inflammatory from the active ingredient in a medicinal plant used throughout Southeast Asia. The novel compound doesn’t suppress the innate immune system like currently used corticosteroids do, open… Continue reading Plant non-steroidal anti-inflammatory leaves immune system intact