Stopping immune system ‘talk’ may provide treatment for severe asthma

People with severe asthma may not respond to the usual treatment. Researchers have examined what drives the inflammatory response in severe asthmatics at a molecular level and their findings may lead to the development of an effective treatment for the… Continue reading Stopping immune system ‘talk’ may provide treatment for severe asthma

Asthma breakthrough uncovers key mechanism behind airway thickening

New research from the La Jolla Institute for Immunology has brought a novel, long-term treatment for severe asthma a step closer. Building on a decade of work, the new findings present a potential way to block the thickening of airway muscle tissue see… Continue reading Asthma breakthrough uncovers key mechanism behind airway thickening

New particle discovered in the bloodstream of patients with sepsis

A brand new type of particle has been discovered in the human bloodstream. The sausage-shaped structures were first found by researchers at La Jolla Institute for Immunology (LJI) in mice with sepsis, and they appear to be related to inflammatory disea… Continue reading New particle discovered in the bloodstream of patients with sepsis

Blood analysis reveals signs of Parkinson’s 10 years before diagnosis

Clumps of a damaged protein called alpha-synuclein gather on the dopamine-producing brain cells of patients with Parkinson's disease, triggering an autoimmune response from T cells

In 2017, scientists at Columbia University found the first direct evidence that autoimmunity may play a role in the onset of Parkinson’s disease. The same team has been working to fill in this timeline of physiological events and uncovered further evidence of how the immune system contributes to the development of the disease, potentially opening up new windows of opportunity for early intervention.

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Continue reading Blood analysis reveals signs of Parkinson’s 10 years before diagnosis