Rogue protein linked to early-onset dementia identified

A visualization of the structure of TAF15 amyloid filaments (in yellow), as detected by cryo-EM in the brains of four dementia patients

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.

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Continue reading Rogue protein linked to early-onset dementia identified