Collaborate Disseminate
Short-lived, acute pain is a normal response to an injury and will steadily diminish as inflammation subsides. For some, however, this kind of pain develops into a chronic condition that persists for more than six months. Scientists have had little und… Continue reading Vitamin B3 may give cells the boost they need to reverse chronic pain
Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and improved the animals’ cognitive functioning. The next step is to develop a drug that can be used in humans.
Tags: Alzheimer’s Disease, Inflammatory, Aging, Yale
Continue reading Drug slows tau’s transformation into toxic tangles seen in Alzheimer’s
There are a lot of research eyes on the development of Polo-like kinase 1 (PLK1) inhibitors for cancer treatment right now, with several drugs currently in clinical trials and at least one in late-stage Phase III testing. But University of Cambridge sc… Continue reading Promising cancer drug may effectively treat gout and heart disease
Researchers investigating the genetics underlying the airway inflammation seen in severe asthma have, for the first time, discovered that proteins that bind to RNA are dysregulated, and drive changes in gene expression in the cells that line the airways.
Tags: RNA, Asthma, Inflammatory, King’s College London
Continue reading RNA-binding proteins discovered to be key to severe asthma
A new study has found that methotrexate, a widely available and affordable drug that’s usually prescribed as a first-line treatment for rheumatoid arthritis, is effective at reducing the pain and stiffness suffered by people with hand osteoarthritis. U… Continue reading Hand osteoarthritis symptoms relieved by an affordable existing drug
New research from a team at the University of Maryland School of Medicine (UMSOM) has for the first time shown how inflammation in early childhood can affect brain development and contribute to the risk of autism spectrum disorders (ASD) and schizophre… Continue reading How inflammation in early childhood can lead to autism and schizophrenia
When diagnosing type 2 diabetes, physicians can look for a range of typical symptoms such as frequent urination and excessive thirst. Now, researchers say the development of other illnesses in the body might need to be added in as a predictive tool.Con… Continue reading Previous illnesses might point to future diabetes risk, says study
Researchers have found that millions worldwide carry a gene variant that controls ‘explosive’ cell death linked to inflammation. They say it may explain why some people are prone to developing inflammatory diseases and potentially lead to the developme… Continue reading “Explosive” cell death gene variant carried by millions of people
Researchers have called for a review of current recommendations for treatment of hand osteoarthritis, after a broad study revealed that injections were shown to be as effective as a placebo in relieving pain. Looking at 72 studies involving 7,609 parti… Continue reading Call to revise hand arthritis treatments due to efficacy concerns
Researchers have found that an intranasal immunotherapy drug, currently being tested as a treatment for multiple sclerosis, reduced brain inflammation and improved cognition in mice with Alzheimer’s disease, independent of the amount of beta-amyloid plaques present. They say the treatment could benefit people in the later stages of the disease.
Tags: Alzheimer’s Disease, Brain, Inflammatory, antibodies, Brigham and Women’s Hospital
Continue reading Nasal Alzheimer’s drug effective regardless of brain plaque levels