Collaborate Disseminate
Researchers investigating the genetics underlying the airway inflammation seen in severe asthma have, for the first time, discovered that proteins that bind to RNA are dysregulated, and drive changes in gene expression in the cells that line the airways.
Tags: RNA, Asthma, Inflammatory, King’s College London
Continue reading RNA-binding proteins discovered to be key to severe asthma
A new study has found that methotrexate, a widely available and affordable drug that’s usually prescribed as a first-line treatment for rheumatoid arthritis, is effective at reducing the pain and stiffness suffered by people with hand osteoarthritis. U… Continue reading Hand osteoarthritis symptoms relieved by an affordable existing drug
New research from a team at the University of Maryland School of Medicine (UMSOM) has for the first time shown how inflammation in early childhood can affect brain development and contribute to the risk of autism spectrum disorders (ASD) and schizophre… Continue reading How inflammation in early childhood can lead to autism and schizophrenia
When diagnosing type 2 diabetes, physicians can look for a range of typical symptoms such as frequent urination and excessive thirst. Now, researchers say the development of other illnesses in the body might need to be added in as a predictive tool.Con… Continue reading Previous illnesses might point to future diabetes risk, says study
Researchers have found that millions worldwide carry a gene variant that controls ‘explosive’ cell death linked to inflammation. They say it may explain why some people are prone to developing inflammatory diseases and potentially lead to the developme… Continue reading “Explosive” cell death gene variant carried by millions of people
Researchers have called for a review of current recommendations for treatment of hand osteoarthritis, after a broad study revealed that injections were shown to be as effective as a placebo in relieving pain. Looking at 72 studies involving 7,609 parti… Continue reading Call to revise hand arthritis treatments due to efficacy concerns
Researchers have found that an intranasal immunotherapy drug, currently being tested as a treatment for multiple sclerosis, reduced brain inflammation and improved cognition in mice with Alzheimer’s disease, independent of the amount of beta-amyloid plaques present. They say the treatment could benefit people in the later stages of the disease.
Tags: Alzheimer’s Disease, Brain, Inflammatory, antibodies, Brigham and Women’s Hospital
Continue reading Nasal Alzheimer’s drug effective regardless of brain plaque levels
According to the Crohn’s & Colitis Foundation, 1.6 million Americans have irritable bowel disease (IBD), with the numbers increasing each year. Around 70,000 new cases are diagnosed annually.
Tags: King’s College London, irritable-bowel-disease, Chronic, Cells, The Immune System, Immunotherapy, Gut Bacteria, Inflammatory, Cancer
Continue reading Immune cell discovery offers hope for irritable bowel disease sufferers
A new study has found that taking cholesterol-lowering statins was associated with a lowered risk of developing colorectal cancer in people with ulcerative colitis. The researchers say that statins, commonly prescribed for heart health, could be used a… Continue reading Statins linked to reduced cancer risk in people with ulcerative colitis
A new study has identified the mechanism that makes all cannabinoids, but particularly CBD, effective at reducing inflammation. The discovery could lead to the development of new therapeutic strategies for the treatment of inflammatory diseases like as… Continue reading Mechanism behind CBD’s potent anti-inflammatory effects identified