Inflammatory – Page 2 – WindowsTechs.com

GLP-1 weight-loss drugs may pivot to treat Alzheimer’s and Parkinson’s

Posted on February 2, 2024 by Bronwyn Thompson

Scientists are still discovering the potential medical 'superpowers' of GLP-1 receptor agonist drugs

In yet another surprise attribute of the new class of obesity drugs, scientists have found that GLP-1 receptor agonists can also subdue brain inflammation, giving them a potential ‘superpower’ in the fight against Alzheimer’s and Parkinson’s diseases.

Category: Medical, Science

Tags: University of Toronto, Ozempic, GLP1, Alzheimer’s Disease, Parkinson’s Disease, Inflammatory, Brain, Dementia

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Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%

Posted on January 5, 2024 by Paul McClure

By fitting microparticle ‘backpacks’ to important inflammatory cells called macrophages, researchers significantly reduced lesion size and inflammation caused by traumatic brain injury. Working with biology rather than against it, this novel approach h… Continue reading Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%→

Plant non-steroidal anti-inflammatory leaves immune system intact

Posted on January 2, 2024 by Paul McClure

Researchers have developed a novel non-steroidal anti-inflammatory from the active ingredient in a medicinal plant used throughout Southeast Asia. The novel compound doesn’t suppress the innate immune system like currently used corticosteroids do, open… Continue reading Plant non-steroidal anti-inflammatory leaves immune system intact→

MS drug to treat and repair nerve damage is edging closer to reality

Posted on December 11, 2023 by Bronwyn Thompson

Effective targeted treatment of multiple sclerosis (MS) and even the repair of damaged nerves caused by the disease could soon be within grasp, thanks to yet another breakthrough in the field of small molecule drug research.Continue ReadingCategory: Me… Continue reading MS drug to treat and repair nerve damage is edging closer to reality→

Biologic therapy shown to reduce steroid use in 92% of severe asthmatics

Posted on December 11, 2023 by Paul McClure

Researchers found that severe asthmatics were able to reduce their dose of inhaled steroids after receiving a biologic therapy

A new study has found that using biologic therapy to reduce lung inflammation enabled 92% of people with severe asthma to reduce their dose of daily inhaled steroid without exacerbating their symptoms. The findings may mean that severe asthmatics can minimize the risk of adverse effects associated with long-term steroid use.

Category: Medical, Science

Tags: Asthma, BioLogic, Inflammatory, King’s College London

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Brain cell gene changes linked to neuroinflammation seen in Alzheimer’s

Posted on November 30, 2023 by Paul McClure

A study has linked genetic changes in the brain's immune cells to the neuroinflammation seen in Alzheimer's disease

New research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.

Category: Medical, Science

Tags: Alzheimer’s Disease, Brain, Inflammatory, Genetics, Brigham and Women’s Hospital

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Overactive inflammation in the brain linked to increased suicide risk

Posted on November 15, 2023 by Paul McClure

A first-of-its-kind study has identified overactive inflammation and loss of critical protective mechanisms in the brain as potential contributors to suicide risk. The findings could lead to the use of anti-inflammatory medications as a way of reducing… Continue reading Overactive inflammation in the brain linked to increased suicide risk→

Vitamin B3 may give cells the boost they need to reverse chronic pain

Posted on November 9, 2023 by Bronwyn Thompson

Short-lived, acute pain is a normal response to an injury and will steadily diminish as inflammation subsides. For some, however, this kind of pain develops into a chronic condition that persists for more than six months. Scientists have had little und… Continue reading Vitamin B3 may give cells the boost they need to reverse chronic pain→

Drug slows tau’s transformation into toxic tangles seen in Alzheimer’s

Posted on November 9, 2023 by Paul McClure

Researchers have used an experimental drug to slow the phosphorylation of tau, which causes it to aggregate into neuron-damaging tangles in Alzheimer's disease

Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and improved the animals’ cognitive functioning. The next step is to develop a drug that can be used in humans.

Category: Medical, Science

Tags: Alzheimer’s Disease, Inflammatory, Aging, Yale

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Promising cancer drug may effectively treat gout and heart disease

Posted on November 2, 2023 by Bronwyn Thompson

There are a lot of research eyes on the development of Polo-like kinase 1 (PLK1) inhibitors for cancer treatment right now, with several drugs currently in clinical trials and at least one in late-stage Phase III testing. But University of Cambridge sc… Continue reading Promising cancer drug may effectively treat gout and heart disease→