Existing jab offers “ray of hope” for preventing rheumatoid arthritis

Abatacept has had a significant impact in preventing or delaying the onset of arthritis for those most at risk

A drug currently used as a second- or third-line treatment for those with rheumatoid arthritis has shown huge promise as a preventative, stopping the onset of the debilitating disease in 92.8% of at-risk participants after 12 months.

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GLP-1 weight-loss drugs may pivot to treat Alzheimer’s and Parkinson’s

Scientists are still discovering the potential medical 'superpowers' of GLP-1 receptor agonist drugs

In yet another surprise attribute of the new class of obesity drugs, scientists have found that GLP-1 receptor agonists can also subdue brain inflammation, giving them a potential ‘superpower’ in the fight against Alzheimer’s and Parkinson’s diseases.

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Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%

By fitting microparticle ‘backpacks’ to important inflammatory cells called macrophages, researchers significantly reduced lesion size and inflammation caused by traumatic brain injury. Working with biology rather than against it, this novel approach h… Continue reading Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%

Plant non-steroidal anti-inflammatory leaves immune system intact

Researchers have developed a novel non-steroidal anti-inflammatory from the active ingredient in a medicinal plant used throughout Southeast Asia. The novel compound doesn’t suppress the innate immune system like currently used corticosteroids do, open… Continue reading Plant non-steroidal anti-inflammatory leaves immune system intact

MS drug to treat and repair nerve damage is edging closer to reality

Effective targeted treatment of multiple sclerosis (MS) and even the repair of damaged nerves caused by the disease could soon be within grasp, thanks to yet another breakthrough in the field of small molecule drug research.Continue ReadingCategory: Me… Continue reading MS drug to treat and repair nerve damage is edging closer to reality

Biologic therapy shown to reduce steroid use in 92% of severe asthmatics

Researchers found that severe asthmatics were able to reduce their dose of inhaled steroids after receiving a biologic therapy

A new study has found that using biologic therapy to reduce lung inflammation enabled 92% of people with severe asthma to reduce their dose of daily inhaled steroid without exacerbating their symptoms. The findings may mean that severe asthmatics can minimize the risk of adverse effects associated with long-term steroid use.

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Brain cell gene changes linked to neuroinflammation seen in Alzheimer’s

A study has linked genetic changes in the brain's immune cells to the neuroinflammation seen in Alzheimer's disease

New research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.

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Overactive inflammation in the brain linked to increased suicide risk

A first-of-its-kind study has identified overactive inflammation and loss of critical protective mechanisms in the brain as potential contributors to suicide risk. The findings could lead to the use of anti-inflammatory medications as a way of reducing… Continue reading Overactive inflammation in the brain linked to increased suicide risk

Vitamin B3 may give cells the boost they need to reverse chronic pain

Short-lived, acute pain is a normal response to an injury and will steadily diminish as inflammation subsides. For some, however, this kind of pain develops into a chronic condition that persists for more than six months. Scientists have had little und… Continue reading Vitamin B3 may give cells the boost they need to reverse chronic pain

Drug slows tau’s transformation into toxic tangles seen in Alzheimer’s

Researchers have used an experimental drug to slow the phosphorylation of tau, which causes it to aggregate into neuron-damaging tangles in Alzheimer's disease

Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and improved the animals’ cognitive functioning. The next step is to develop a drug that can be used in humans.

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