Too much ‘good’ cholesterol could be bad for dementia, says study

It’s generally considered a good thing to have elevated levels of HDL cholesterol, also commonly referred to as “good” cholesterol. But new research indicates that when those HDL levels climb too high, dementia could be an unwanted side effect.Continue… Continue reading Too much ‘good’ cholesterol could be bad for dementia, says study

One-off gene-editing treatment lowers inherited bad cholesterol levels

Researchers have presented the interim results of a clinical trial that used a single infusion of CRISPR gene-editing technology to permanently switch off low-density lipoprotein cholesterol production in people with a genetic condition that causes ele… Continue reading One-off gene-editing treatment lowers inherited bad cholesterol levels

One-dose drug reduced genetic bad cholesterol by 94% for almost a year

Researchers have conducted the first human trials of a new drug, lepodisiran, and found that a single injection reduced lipoprotein(a) – a ‘bad’ cholesterol with a genetic basis – to undetectable levels for almost a year. It has the potential to elimin… Continue reading One-dose drug reduced genetic bad cholesterol by 94% for almost a year

Key discovery opens new avenue to lowering cholesterol levels

Researchers have identified a previously unknown step in the process by which dietary cholesterol is absorbed from the intestine into the bloodstream. The newfound pathway provides a potential new target for treating high cholesterol.Continue ReadingCa… Continue reading Key discovery opens new avenue to lowering cholesterol levels

Common dietary nutrient blasts blood vessel plaques in study

While statin drugs are good at controlling plaques in blood vessels, they can’t eliminate them once they are established. But researchers may have just found a way to blast the circulatory system clean using a common nutrient found in many foods.Contin… Continue reading Common dietary nutrient blasts blood vessel plaques in study

World-first drug lowers genetic form of “bad cholesterol” by up to 65%

A groundbreaking oral drug has been developed that lowers lipoprotein(a), a previously untreatable largely inherited form of 'bad cholesterol'

Researchers have developed the world’s first oral drug to target a form of cholesterol that has previously been untreatable and is largely caused by genetics, making it difficult to control by way of exercise, diet or other lifestyle factors.

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Continue reading World-first drug lowers genetic form of “bad cholesterol” by up to 65%

Gene mutation that can lead to heart disease identified

For the first time, scientists have discovered how a gene mutation can cause heart disease in adults despite normal cholesterol levels and no other risk factors.Continue ReadingCategory: Medical, ScienceTags: University of Texas, Heart Disease, Heart a… Continue reading Gene mutation that can lead to heart disease identified

‘Silent’ killer in cholesterol more firmly linked to heart disease

A genetic ‘bad’ cholesterol protein has been flagged as a hidden problem in coronary heart disease (CHD), with current medication that treats low-density lipoproteins (LDL) having little effect on this particular variant.Continue ReadingCategory: Medic… Continue reading ‘Silent’ killer in cholesterol more firmly linked to heart disease

Oral pill cuts bad cholesterol by 60% in phase 2 clinical trial

High cholesterol levels are a common and potentially deadly health problem, but a new drug could help more people manage the condition. An experimental pill has been shown to reduce levels of “bad” cholesterol by 60% in a phase 2 clinical trial.Continu… Continue reading Oral pill cuts bad cholesterol by 60% in phase 2 clinical trial

NIH study casts doubts on heart benefits of “good” cholesterol

For half a century cholesterol has been divided into good and bad categories. Low-density lipoprotein (LDL) is considered the “bad” cholesterol as it’s responsible for blocking arteries and causing stroke or heart attacks, while high-density lipoprotei… Continue reading NIH study casts doubts on heart benefits of “good” cholesterol