Discovery of genetic connection between Alzheimer’s and gut disorders

A new study has established a genetic link between Alzheimer's and gut disorders

Research continues to demonstrate the many ways the gut microbiome can influence human health, and an active area within this field centers on its role in Alzheimer’s disease (AD). A new study has furthered our knowledge of this relationship by demonstrating what’s described as a clear genetic link between the two, while also pointing to the potential for new treatments.

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Non-invasive scanning tech reads blood cholesterol levels via the skin

For people with coronary heart disease, regular monitoring of bloodstream cholesterol levels is essential – and it typically requires the drawing of blood samples. A new system, however, is claimed to provide the same data simply by imaging the skin of… Continue reading Non-invasive scanning tech reads blood cholesterol levels via the skin

Statins unlikely to prevent severe COVID-19, Johns Hopkins study finds

New research led by a team from Johns Hopkins Medicine has found no evidence statin use can reduce a person’s risk of severe COVID-19 or death. Countering several small studies suggesting statins may be somewhat protective against severe COVID-19, the … Continue reading Statins unlikely to prevent severe COVID-19, Johns Hopkins study finds

Researchers discover how cholesterol feeds cancer metastasis

New research led by the Duke Cancer Institute has identified one of the ways cholesterol can enhance the ability of cancer cells to metastasize. The study focused particularly on breast cancer, shedding light on prior observational research linking sta… Continue reading Researchers discover how cholesterol feeds cancer metastasis

Can Alzheimer’s be tackled by cutting cholesterol in the brain?

Scientists have uncovered a mechanism that may allow Alzheimer's to be tackled by controlling cholesterol levels in the brain

One interesting area of Alzheimer’s research focuses on the relationship between cholesterol in the brain and onset of the disease, with studies suggesting the compound can greatly accelerate the buildup of troublesome brain plaques. A new study has expanded our knowledge of this phenomenon by observing it in action in live mice, with the scientists even finding they could intervene in cholesterol production to make the plaques all but disappear.

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Experimental drug halves cholesterol levels in phase 2 clinical trials

Scientists are reporting promising results from a phase 2 clinical trial of a cholesterol-reducing drug called evinacumab. The study reports that in patients with extremely high cholesterol, the drug was able to reduce levels by about half, compared to… Continue reading Experimental drug halves cholesterol levels in phase 2 clinical trials

Subtype of autism linked with abnormal cholesterol levels identified

Researchers have identified a subtype of autism and will examine if it can be treated with cholesterol-lowering drugs like statins

Using a novel multi-modal approach to data analysis, scientists have identified a specific subtype of autism linked with a gene cluster known to affect both neurodevelopment and lipid metabolism. The research suggests this subtype could account for nearly seven percent of autism cases and future study will explore whether cholesterol-lowering drugs such as statins could be an effective treatment.

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Protein pair form entry tunnel for bad cholesterol to enter cells

While some cholesterol is a healthy thing for properly functioning cells, too much of it can cause blockages in the arteries and heart trouble, along with a host of other negative health outcomes. Scientists have discovered a new mechanism by which a “… Continue reading Protein pair form entry tunnel for bad cholesterol to enter cells

How gut bacteria can break down cholesterol to improve cardiac health

An impressively rigorous new study, led by researchers at the Broad Institute of MIT and Harvard, is shedding light on a century-old mystery. The study describes how bacteria in the gut can metabolize cholesterol at levels high enough to improve a pers… Continue reading How gut bacteria can break down cholesterol to improve cardiac health

New molecules rebalance gut bacteria to cut cholesterol in mice

Recent research is continuing to illuminate the role gut bacteria can play in all sorts of health outcomes, uncovering its ties with depression, obesity and various autoimmune diseases, just to offer a few examples. A new study has delved into their im… Continue reading New molecules rebalance gut bacteria to cut cholesterol in mice