Remote indigenous Amazon tribe has lowest dementia rates in the world

An isolated tribe in the Bolivian Amazon was previously also found to have the healthiest arteries of any population ever studied

Researchers working with remote indigenous populations in the Bolivian Amazon have found the communities experience extraordinarily low rates of dementia. The new study follows on from prior findings reporting the same groups display almost no cases of age-related heart disease.

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Increased dementia risk in women linked to early menopause

Very early onset of menopause was linked to a 35 percent increased risk of developing dementia

New research presented at the American Heart Association’s Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022 has found women who experience very early menopause are significantly more likely to develop dementia in later life.

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The new science linking cancer, schizophrenia and MS to viral infections

Researchers have found a number of chronic or age-related diseases may be influenced by persistent viral infections

We are all very familiar now with the way viral infections lead to acute disease. From the flu to COVID-19 and the measles, it is well understood how viruses lead to disease but scientists are only now discovering the broad role viral infections play in the development of other health conditions, often emerging years or even decades after the initial infection.

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Bacteria could travel from the nose to the brain and trigger Alzheimer’s

A new study has found evidence that nose bacteria could move into the brain through the nerves and trigger a cascade of events that can lead to Alzheimer's disease

Researchers in Australia have found evidence that bacteria that live in the nose can make their way into the brain through nasal cavity nerves, setting off a series of events that could lead to Alzheimer’s disease. The work adds to the growing body of evidence that Alzheimer’s may be initially triggered through viral or bacterial infections.

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Age-related cognitive decline linked with buildup of iron in the brain

New research homes in on a mechanism that could explain how brain iron levels increase with age

Researchers at Northwestern Western have uncovered a mechanism they say contributes to the age-related accumulation of iron in the brain, a process some argue is a cause of cognitive decline. The study bolsters the hypothesis that reducing brain iron levels could combat neurodegenerative diseases such as Alzheimer’s.

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Stalled Alzheimer’s drug may find new purpose against superbugs

Researchers have repurposed an experimental Alzheimer's drug to fight antibiotic-resistant bacteria

Our antibiotics are failing in large numbers, threatening a future “dark age of medicine” where once-simple infections become lethal again. A team of scientists has now found a way to restore common antibiotics to their former strength, by repurposing a molecule developed to treat Alzheimer’s.

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Brain tissue study sheds light on how exercise can fight dementia

Researchers have linked physical activity to higher levels of presynaptic proteins in the brain

A new post-mortem brain tissue study is offering clues as to how exercise in old age can improve brain health and prevent cognitive decline. The research found late-life physical activity was associated with higher levels of presynaptic proteins, molecules previously found to support healthy brain functions.

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Dementia-preventing nasal spray moves to human trials

A novel nasal spray combines a common antibiotic with a well-known antioxidant and human trials are set to begin soon

Scientists from Osaka City University are reporting successful preclinical tests of a novel nasal spray designed to prevent the neurodegeneration associated with dementia. The spray combines two cheap, pre-existing drugs and was found to improve cognitive function in several different mouse models of dementia.

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Poor oral health linked to wide variety of diseases and mental illness

Examining health records from more than 60,000 people, researchers found gum disease increased a person's risk of developing a number of illnesses

In one of the largest studies of its kind to date UK researchers have found gum disease to be associated with an increased risk of developing cardiovascular and autoimmune disease. The findings build on a growing body of research linking poor oral health with broader chronic disease.

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How gym junkie mice could inspire a new therapy for dementia

The researchers homed in on an exercise-induced protein called clusterin and suspect it has anti-inflammatory properties helping tamp down neuroinflammation and improving cognition

We know exercise is good for the brain, but we don’t know exactly how exercise improves brain health. A new Stanford study has homed in on a single anti-inflammatory protein that seems to increase in the blood with exercise and the findings could inspire new kinds of drugs that prevent neurodegeneration or cognitive decline.

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