Alzheimer’s Disease – Page 14

Alpaca nanobodies target and dissolve root cause of chronic inflammation

Posted on April 20, 2022 by Nick Lavars

Alpaca immune systems have some properties that may be very useful to medical science

By tapping into the unique immune system of alpacas, scientists have developed a promising technique for tempering chronic inflammation associated with conditions such as arthritis. The breakthrough hinges on what are known as nanobodies, which when taken from the woolly mammals were shown to neutralize the alarm system for the immune system and, in doing so, treat excessive inflammation in unhealthy mice.

Category: Medical, Science

Tags: Inflammatory, Arthritis, Rheumatoid arthritis, Bonn University, Alzheimer’s Disease

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New hypothesis argues leaky blood-brain barrier triggers Alzheimer’s

Posted on April 11, 2022 by Rich Haridy

A new hypothesis proposes fatty molecules in the blood stream invade the brain through a leaky blood brain barrier and this processes triggers Alzheimer's disease

A new article in the Journal of Alzheimer’s Disease Reports has proposed a novel hypothesis for the cause of Alzheimer’s disease. The article argues Alzheimer’s is caused by a damaged blood-brain barrier allowing fatty molecules known as lipids to invade the brain and trigger a cascade of events that result in neurodegeneration and cognitive decline.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Brain, Blood-brain barrier, University of Reading, Fat cells, Neuroscience

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Alzheimer’s-preventing nasal spray targets novel brain mechanism

Posted on April 7, 2022 by Rich Haridy

A nasal spray has been developed to inhibit a brain mechanism hypothesized to be an early driver of Alzheimer's disease

An international team of researchers has reported on the successful preclinical tests of a novel nasal spray developed to prevent neurodegeneration associated with Alzheimer’s disease. The treatment was effective at reversing the pathological signs of Alzheimer’s in mouse models and the researchers are looking to start human tests in two years.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Brain, Neuroscience, New Atlas Audio

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Landmark study finds 42 new genetic risk factors for Alzheimer’s disease

Posted on April 5, 2022 by Rich Haridy

New research has discovered more than 40 genetic regions previously not associated with Alzheimer's disease risk

A milestone study involving hundreds of scientists from around the world has identified 75 genomic regions associated with Alzheimer’s disease. A number of the newly discovered genetic pathways play a role in inflammation, adding weight to a growing hypothesis immune dysfunction can drive disease progression. Plus, the researchers raise the possibility of developing an Alzheimer’s genetic risk test to predict those most likely to develop the neurodegenerative condition.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Brain, Genetics, Cardiff University, Neuroscience

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Excessive daytime napping could be early sign of Alzheimer’s disease

Posted on March 18, 2022 by Rich Haridy

Napping for more than one hour or more than once a day has been linked to Alzheimer's

Napping for longer than one hour or several times a day could be an early sign of Alzheimer’s disease according to new research. It’s suggested excessive daytime napping shares a bidirectional relationship with cognitive decline, both reflecting and shaping changes in the brain.

Category: Health & Wellbeing, Lifestyle

Tags: Sleeping, Sleep, Alzheimer’s Disease, Dementia, Aging, Brain, UCSF, Brigham and Women’s Hospital, New Atlas Audio

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“Elite sleeper” gene study offers hope for novel dementia treatment

Posted on March 16, 2022 by Rich Haridy

New research indicates people with the ability to sleep as little as four hours a night and remain healthy may harbor gene variants that can slow neurodegeneration

Are you one of those lucky people who seem to be able to thrive on between four and six hours of sleep per night? You may be what UC San Francisco researchers have dubbed an “elite sleeper,” and a new study reports the same genes associated with healthy short sleep patterns may also slow the onset of neurodegenerative diseases such as Alzheimer’s.

Category: Health & Wellbeing, Lifestyle

Tags: Sleep, Sleeping, Genetics, Dementia, Alzheimer’s Disease, Brain, UCSF, New Atlas Audio

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Remote indigenous Amazon tribe has lowest dementia rates in the world

Posted on March 10, 2022 by Rich Haridy

An isolated tribe in the Bolivian Amazon was previously also found to have the healthiest arteries of any population ever studied

Researchers working with remote indigenous populations in the Bolivian Amazon have found the communities experience extraordinarily low rates of dementia. The new study follows on from prior findings reporting the same groups display almost no cases of age-related heart disease.

Category: Health & Wellbeing, Lifestyle

Tags: Dementia, University of Southern California, Alzheimer’s Disease, Parkinson’s Disease

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Increased dementia risk in women linked to early menopause

Posted on March 2, 2022 by Rich Haridy

Very early onset of menopause was linked to a 35 percent increased risk of developing dementia

New research presented at the American Heart Association’s Epidemiology, Prevention, Lifestyle & Cardiometabolic Health Conference 2022 has found women who experience very early menopause are significantly more likely to develop dementia in later life.

Category: Health & Wellbeing, Lifestyle

Tags: Aging, Women, Dementia, Alzheimer’s Disease, Brain, Menopause, Hormone, New Atlas Audio

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The new science linking cancer, schizophrenia and MS to viral infections

Posted on February 25, 2022 by Rich Haridy

Researchers have found a number of chronic or age-related diseases may be influenced by persistent viral infections

We are all very familiar now with the way viral infections lead to acute disease. From the flu to COVID-19 and the measles, it is well understood how viruses lead to disease but scientists are only now discovering the broad role viral infections play in the development of other health conditions, often emerging years or even decades after the initial infection.

Category: Science

Tags: Virus, Vaccines, Cancer, Alzheimer’s Disease, Schizophrenia, Multiple Sclerosis

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Bacteria could travel from the nose to the brain and trigger Alzheimer’s

Posted on February 18, 2022 by Michael Irving

A new study has found evidence that nose bacteria could move into the brain through the nerves and trigger a cascade of events that can lead to Alzheimer's disease

Researchers in Australia have found evidence that bacteria that live in the nose can make their way into the brain through nasal cavity nerves, setting off a series of events that could lead to Alzheimer’s disease. The work adds to the growing body of evidence that Alzheimer’s may be initially triggered through viral or bacterial infections.

Category: Medical, Science

Tags: Alzheimer’s Disease, Disease, Bacteria, Brain, Neuroscience, Griffith University, Queensland University of Technology, New Atlas Audio

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