Protein derived from corn boosts memory in mice with Alzheimer’s

Scientists have used a protein derived from corn as the basis for a potential vaccine for Alzheimer's

Among the many ways scientists hope to be able to tackle Alzheimer’s is by preventing it from taking hold in the first place, or at least averting its worst effects. This idea of a vaccine for Alzheimer’s is gaining traction as scientists continue to devise new ways of clearing the brain of toxic proteins hypothesized to be key drivers of the condition. A newly published study has hinted at further possibilities in this area, with a protein derived from corn used to induce an immune response and improve memory in mice with the disease.

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Pupil-tracking smartphone app looks to catch early-stage Alzheimer’s

Using the selfie camera and the front-facing near-infrared camera, a smartphone app could assess cognitive condition

A prototype smartphone app has been developed to screen for the very earliest stages of Alzheimer’s disease. The app tracks minute changes in a person’s pupil size, which previous research has shown can indicate pre-clinical neurological disease.

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Study finds seven hours of sleep to be optimal from middle-age onwards

A new study suggests that seven hours of sleep per night is best for brain health in middle and old age

We know sleep to be an essential ingredient for a healthy brain, but scientists continue to explore what a good night’s rest looks like at different stages of life, and how it can impact on our vulnerability to cognitive decline. A wide-ranging new study involving almost half a million subjects has provided compelling new insights, suggesting seven hours of sleep per night to be best for brain health during middle and old age.

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New study may explain why apathy is the first symptom of Alzheimer’s

New research hypothesizes degeneration in a brain region called the nucleus accumbens could trigger apathy, the earliest psychiatric sign of Alzheimer's disease

Compelling new research from the Indiana University School of Medicine has homed in on a degenerative mechanism that could explain why symptoms such as apathy are the first signs of Alzheimer’s disease. The findings suggest disrupting this process could slow the progression of Alzheimer’s-related dementia.

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Alpaca nanobodies target and dissolve root cause of chronic inflammation

Alpaca immune systems have some properties that may be very useful to medical science

By tapping into the unique immune system of alpacas, scientists have developed a promising technique for tempering chronic inflammation associated with conditions such as arthritis. The breakthrough hinges on what are known as nanobodies, which when taken from the woolly mammals were shown to neutralize the alarm system for the immune system and, in doing so, treat excessive inflammation in unhealthy mice.

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New hypothesis argues leaky blood-brain barrier triggers Alzheimer’s

A new hypothesis proposes fatty molecules in the blood stream invade the brain through a leaky blood brain barrier and this processes triggers Alzheimer's disease

A new article in the Journal of Alzheimer’s Disease Reports has proposed a novel hypothesis for the cause of Alzheimer’s disease. The article argues Alzheimer’s is caused by a damaged blood-brain barrier allowing fatty molecules known as lipids to invade the brain and trigger a cascade of events that result in neurodegeneration and cognitive decline.

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Alzheimer’s-preventing nasal spray targets novel brain mechanism

A nasal spray has been developed to inhibit a brain mechanism hypothesized to be an early driver of Alzheimer's disease

An international team of researchers has reported on the successful preclinical tests of a novel nasal spray developed to prevent neurodegeneration associated with Alzheimer’s disease. The treatment was effective at reversing the pathological signs of Alzheimer’s in mouse models and the researchers are looking to start human tests in two years.

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Landmark study finds 42 new genetic risk factors for Alzheimer’s disease

New research has discovered more than 40 genetic regions previously not associated with Alzheimer's disease risk

A milestone study involving hundreds of scientists from around the world has identified 75 genomic regions associated with Alzheimer’s disease. A number of the newly discovered genetic pathways play a role in inflammation, adding weight to a growing hypothesis immune dysfunction can drive disease progression. Plus, the researchers raise the possibility of developing an Alzheimer’s genetic risk test to predict those most likely to develop the neurodegenerative condition.

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Excessive daytime napping could be early sign of Alzheimer’s disease

Napping for more than one hour or more than once a day has been linked to Alzheimer's

Napping for longer than one hour or several times a day could be an early sign of Alzheimer’s disease according to new research. It’s suggested excessive daytime napping shares a bidirectional relationship with cognitive decline, both reflecting and shaping changes in the brain.

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“Elite sleeper” gene study offers hope for novel dementia treatment

New research indicates people with the ability to sleep as little as four hours a night and remain healthy may harbor gene variants that can slow neurodegeneration

Are you one of those lucky people who seem to be able to thrive on between four and six hours of sleep per night? You may be what UC San Francisco researchers have dubbed an “elite sleeper,” and a new study reports the same genes associated with healthy short sleep patterns may also slow the onset of neurodegenerative diseases such as Alzheimer’s.

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