Selective cell ‘hit jobs’ aim to reverse age-related conditions

Senescent cells have been the number-one target for scientists seeking the elusive magic bullet in anti-aging therapy. And with good reason: as we age, these old, dysfunctional, non-dividing cells become increasingly harder for the immune system to dis… Continue reading Selective cell ‘hit jobs’ aim to reverse age-related conditions

Call to revise hand arthritis treatments due to efficacy concerns

Researchers have called for a review of current recommendations for treatment of hand osteoarthritis, after a broad study revealed that injections were shown to be as effective as a placebo in relieving pain. Looking at 72 studies involving 7,609 parti… Continue reading Call to revise hand arthritis treatments due to efficacy concerns

Drug that mimics exercise triggers weight loss and builds lean muscle

As a new age of weight-loss therapeutics dawns, heralded by the likes of semaglutide (Ozempic, Wegovy), scientists are one step closer to creating a drug that can coax muscles into behaving as if they’ve just been put through a vigorous workout. Known … Continue reading Drug that mimics exercise triggers weight loss and builds lean muscle

Coffee compound improves age-related decline in memory and learning

A new study has found that a bioactive compound found in coffee beans improved learning and memory decline in aged mice. The findings open the door to developing a supplementary medicinal compound to treat or prevent age-related cognitive decline.Conti… Continue reading Coffee compound improves age-related decline in memory and learning

Calls to address overlooked ADHD in adults aged 50 and over

ADHD symptoms in older adults are often attributed to other conditions or the side effects of medication

There’s growing recognition that attention-deficit hyperactive disorder (ADHD) is not just a disruptive childhood condition, with conservative numbers estimating that 8.7 million adults in the US are living with it, both diagnosed and not. Yet older adults, aged 50 and over, are not only consistently absent from ADHD studies, but face roadblocks if they even try to seek help.

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Novel electrical therapy rebuilds muscles lost through natural aging

Sarcopenia affects up to 16% of the world’s aging population and is one of the leading factors in the loss of independence. Marked by a loss of both muscle mass and function or strength, it’s behind many age-related falls, poor mobility and functional … Continue reading Novel electrical therapy rebuilds muscles lost through natural aging

Improving bone strength by just 3% slashes hip fracture rate by 45%

According to the Centers for Disease Control and Prevention (CDC), more than 300,000 Americans aged 65 and older are hospitalized for hip fractures each year. The major health issues come in the wake of the break. One in three adults over the age of 50… Continue reading Improving bone strength by just 3% slashes hip fracture rate by 45%

New molecule slams the brakes on Alzheimer’s disease inflammation

The brains of Alzheimer's model mice treated with A11 (right) showed more tubulin (yellow), a marker of neuronal health, compared to the untreated mice (left)

In an effort to find new treatments to halt the progression of Alzheimer’s disease, scientists at The Picower Institute for Learning and Memory at the Massachusetts Institute of Technology (MIT) have landed on a molecule that can improve memory by putting the brakes on a process that causes brain inflammation.

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Liesel becomes the first gorilla to have stem-cell therapy for arthritis

In a world first, Budapest Zoo’s gorilla matriarch Liesel has received stem-cell therapy for her arthritis. An international team including University of Sheffield professor Mark Wilkinson, an expert in human arthritis treatment, has used mesenchymal s… Continue reading Liesel becomes the first gorilla to have stem-cell therapy for arthritis

Naked mole-rat’s ‘longevity’ gene extends lifespan and health of mice

They weigh about an ounce, spend their lives underground in sub-Saharan Africa and are unlikely to be making the shortlist for any cute animal calendars, but the naked mole-rat continues to show scientists it has incredible age-resistant biology beneat… Continue reading Naked mole-rat’s ‘longevity’ gene extends lifespan and health of mice