Collaborate Disseminate
Researchers have conducted the first human trials of a new drug, lepodisiran, and found that a single injection reduced lipoprotein(a) – a ‘bad’ cholesterol with a genetic basis – to undetectable levels for almost a year. It has the potential to elimin… Continue reading One-dose drug reduced genetic bad cholesterol by 94% for almost a year
Researchers have identified a blood protein that can be used as a marker of gastric and other cancers and is more accurate than existing diagnostic biomarkers, even in the early stages of the disease. The simple test may lead to the earlier diagnosis o… Continue reading Gastric cancer biomarker nearly 90% accurate, even in early stages
A study has found that a high sensitivity to pain may increase the likelihood that someone will be sympathetic to opposing political views, and may even cause a Trump supporter to vote for Biden and a Biden supporter to vote for Trump.Continue ReadingC… Continue reading People with higher pain sensitivity more likely to vote for ‘other side’
A clinical trial has found that the cardiovascular benefits that the drug semaglutide affords to overweight or obese type 2 diabetics extend to those without diabetes as well. The study suggests that the drug offers a new way to reduce the potentially … Continue reading Ozempic drug found to reduce heart risk in overweight non-diabetics
Researchers have identified a previously unknown step in the process by which dietary cholesterol is absorbed from the intestine into the bloodstream. The newfound pathway provides a potential new target for treating high cholesterol.Continue ReadingCa… Continue reading Key discovery opens new avenue to lowering cholesterol levels
A new study has found that an extract made from willow bark, the precursor to aspirin, possesses effective broad-spectrum antiviral properties. The discovery may mean we will soon have a new way of fighting viral infections, from stomach bugs to season… Continue reading Beyond aspirin: Willow bark also found to be a broad-spectrum antiviral
A new study has found that specific regions of the brain are activated after a drug is taken intravenously but not when the same drug is taken orally, with increased activity correlating to an increased feeling of euphoria. The findings could lead to n… Continue reading Specific brain regions activated by IV drug use but not oral, study finds
Researchers have identified the gene responsible for setting off a cellular chain reaction that causes prostate cancer to metastasize to the bone, making it almost impossible to treat. The discovery could have significant implications for treating pros… Continue reading Genetic ringleader responsible for prostate cancer spread identified
Researchers have discovered a previously unknown pathological cellular mechanism underpinning heart failure, which currently has no cure, and identified a drug that can reverse the damaging malfunction. The findings open the door to a novel interventio… Continue reading Drug found to reverse mitochondria malfunction & mitigate heart failure
Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and improved the animals’ cognitive functioning. The next step is to develop a drug that can be used in humans.
Tags: Alzheimer’s Disease, Inflammatory, Aging, Yale
Continue reading Drug slows tau’s transformation into toxic tangles seen in Alzheimer’s