COVID-19 severity linked to gut bacteria in first-of-its-kind study

A first-of-its-kind study has investigated the relationship between COVID-19 severity and the gut microbiome. The observational research suggests specific microbial patterns correlate with disease severity and those bacterial imbalances may account for… Continue reading COVID-19 severity linked to gut bacteria in first-of-its-kind study

Chronic gut inflammation triggered by e-cigarette use

New research is suggesting e-cigarette vapor alone, free of nicotine or flavoring, can potentially trigger gut inflammation. Across a series of experiments the study demonstrated how e-cigarette vapor can weaken the gut’s lining and lead to chronic inf… Continue reading Chronic gut inflammation triggered by e-cigarette use

Molecular “off” switch keeps cancer immunotherapy from turning deadly

One of the most promising cancer treatments is CAR T cell immunotherapy, where the body’s natural tumor-hunting cells are supercharged – but it can backfire with potentially deadly results. Now, scientists have engineered these immune cells to have off… Continue reading Molecular “off” switch keeps cancer immunotherapy from turning deadly

US and UK diverge over critical COVID-19 vaccine dose strategy

Health authorities in the United Kingdom have recommended extending dosing schedules for approved COVID-19 vaccines, suggesting one dose offers enough short-term protection despite clinical trials only testing two-dose regimes. Authorities in the Unite… Continue reading US and UK diverge over critical COVID-19 vaccine dose strategy

“Triple punch” immunotherapy puts Crohn’s disease into remission in mice

Crohn’s disease is an inflammatory bowel condition, and one suspected cause is the immune system launching an overly-strong response to gut microbes. Now researchers have developed a new kind of immunotherapy for Crohn’s that delivers a “triple punch” … Continue reading “Triple punch” immunotherapy puts Crohn’s disease into remission in mice

Engineered immune cells prevent type 1 diabetes in mouse study

Researchers at the University of Arizona have adapted a form of cancer immunotherapy to develop a new potential treatment for type 1 diabetes. In mouse studies, the team tweaked immune cells to fight off the rogue T cells that damage insulin-producing … Continue reading Engineered immune cells prevent type 1 diabetes in mouse study

New particle discovered in the bloodstream of patients with sepsis

A brand new type of particle has been discovered in the human bloodstream. The sausage-shaped structures were first found by researchers at La Jolla Institute for Immunology (LJI) in mice with sepsis, and they appear to be related to inflammatory disea… Continue reading New particle discovered in the bloodstream of patients with sepsis

Phase 1 human trial for universal flu vaccine reports promising results

Even after decades of research and expansive global vaccination strategies, seasonal influenza still kills hundreds of thousands of people every year. The virus’s ability to mutate and evade our vaccines means we are constantly chasing the latest strai… Continue reading Phase 1 human trial for universal flu vaccine reports promising results

Dormant cancer cells reawakened by stress hormones

Years after a successful treatment cancers can often recur when dormant tumor cells reawaken. Exactly what reactivates these sleeping cancer cells is unknown but a compelling new study is offering a novel hypothesis, suggesting certain stress hormones … Continue reading Dormant cancer cells reawakened by stress hormones

T cells squeeze fresh drugs into cancer in new immunotherapy treatment

Researchers at EPFL have demonstrated a new method to make immunotherapy a more effective and directed treatment against cancer. The team designed microparticles containing drugs that are only released when T cells physically squeeze them, on contact w… Continue reading T cells squeeze fresh drugs into cancer in new immunotherapy treatment