Collaborate Disseminate
Following the emergence of SARS-CoV-2 in 2020 there are now seven different coronaviruses known to infect humans. Four of those are associated with generally harmless common respiratory infections, but the other three (SARS, SARS-CoV-2 and MERS) are mu… Continue reading “Zombie” COVID particles may be responsible for lethal disease
MIT researchers have delivered a type of vaccine called a particulate vaccine to mice using a virus-mimicking scaffold made from particles of DNA instead of the usual protein particles. It not only generated a robust immune response but avoided the off… Continue reading Virus-mimicking DNA particles deliver vaccine without immune side effects
Researchers have developed a peptide that targets a previously ‘undruggable’ protein implicated in more than 75% of human cancers and found that it slowed the proliferation of brain cancer cells in the lab. It’s the first step towards developing an eff… Continue reading “Glob of randomness” linked to 75% of cancers reined in by novel peptide
Inspired by a creature from Greek mythology, researchers have created a ‘two-headed’ drug that prevents the production of the toxic protein linked to Parkinson’s disease before destroying the RNA machinery that makes it. The novel drug may be a way of slowing or even stopping the disease’s progression.
Tags: Parkinson’s Disease, RNA, Protein, Drug, Scripps Research Institute
Continue reading Novel ‘Chimera’ drug targets the ‘undruggable’ Parkinson’s protein
Chinese scientists have developed a cost-effective method of converting coal into protein, which they say could feed livestock much more efficiently than natural plants, while using a tiny fraction of the land.Continue ReadingCategory: ScienceTags: Agr… Continue reading Coal-to-protein livestock feed uses 1/1000th as much land as farming
A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The findings could lead to novel treatments to help treat this debilitating disease.
Tags: Alzheimer’s Disease, Protein, Brain, University of Pennsylvania
Continue reading “Chemical chaperone” improves Alzheimer’s signs in early & late disease
Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune responses. Importantly, they’ve also discovered a so… Continue reading mRNA mod responsible for off-target effects identified & fixed
Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.
Tags: Medical Research Council, Dementia, Alzheimer’s Disease, Protein, Brain, Neuroscience, Neurological
Continue reading Rogue protein linked to early-onset dementia identified
A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeu… Continue reading Protein discovery raises prospect of treatment for COPD
A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeu… Continue reading Protein discovery raises prospect of treatment for COPD