Collaborate Disseminate
Perhaps one of the most persistent debates around COVID has been the reason behind the disease’s neurological symptoms. Ever since SARS-CoV-2 emerged in late 2019 the virus has been known for its novel effects on the brain: Extreme fatigue, cognitive a… Continue reading Inflammation or infection: The debate over COVID’s effect on the brain
Researchers have developed drug-loaded nanoparticles that selectively target the cells responsible for causing damaging inflammation following a spinal cord injury. Given to mice soon after an injury, the novel therapy reduced inflammation and improved… Continue reading Drug-loaded nanoparticles may prevent paralysis from spinal cord injury
A drug currently used as a second- or third-line treatment for those with rheumatoid arthritis has shown huge promise as a preventative, stopping the onset of the debilitating disease in 92.8% of at-risk participants after 12 months.
Tags: King’s College London, Arthritis, Rheumatoid arthritis, Pain, Joints, Inflammatory, Aging, Age-Related
Continue reading Existing jab offers “ray of hope” for preventing rheumatoid arthritis
In yet another surprise attribute of the new class of obesity drugs, scientists have found that GLP-1 receptor agonists can also subdue brain inflammation, giving them a potential ‘superpower’ in the fight against Alzheimer’s and Parkinson’s diseases.
Tags: University of Toronto, Ozempic, GLP1, Alzheimer’s Disease, Parkinson’s Disease, Inflammatory, Brain, Dementia
Continue reading GLP-1 weight-loss drugs may pivot to treat Alzheimer’s and Parkinson’s
By fitting microparticle ‘backpacks’ to important inflammatory cells called macrophages, researchers significantly reduced lesion size and inflammation caused by traumatic brain injury. Working with biology rather than against it, this novel approach h… Continue reading Cells wearing ‘backpacks’ shrink traumatic brain injury lesions by 56%
Researchers have developed a novel non-steroidal anti-inflammatory from the active ingredient in a medicinal plant used throughout Southeast Asia. The novel compound doesn’t suppress the innate immune system like currently used corticosteroids do, open… Continue reading Plant non-steroidal anti-inflammatory leaves immune system intact
Effective targeted treatment of multiple sclerosis (MS) and even the repair of damaged nerves caused by the disease could soon be within grasp, thanks to yet another breakthrough in the field of small molecule drug research.Continue ReadingCategory: Me… Continue reading MS drug to treat and repair nerve damage is edging closer to reality
A new study has found that using biologic therapy to reduce lung inflammation enabled 92% of people with severe asthma to reduce their dose of daily inhaled steroid without exacerbating their symptoms. The findings may mean that severe asthmatics can minimize the risk of adverse effects associated with long-term steroid use.
Tags: Asthma, BioLogic, Inflammatory, King’s College London
Continue reading Biologic therapy shown to reduce steroid use in 92% of severe asthmatics
New research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.
Tags: Alzheimer’s Disease, Brain, Inflammatory, Genetics, Brigham and Women’s Hospital
Continue reading Brain cell gene changes linked to neuroinflammation seen in Alzheimer’s
A first-of-its-kind study has identified overactive inflammation and loss of critical protective mechanisms in the brain as potential contributors to suicide risk. The findings could lead to the use of anti-inflammatory medications as a way of reducing… Continue reading Overactive inflammation in the brain linked to increased suicide risk