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Researchers in Ireland have developed a new gene therapy treatment that may be able to save the vision of patients with a genetic disease that can lead to blindness. The condition, known as dominant optic atrophy (DOA), currently has no preventative or… Continue reading Gene therapy may help prevent vision loss from genetic eye disease
The CRISPR/Cas9 gene-editing tool has shown promise in treating a wide range of diseases, but getting it into cells in the first place can be challenging. Now, researchers in Australia have packaged the tool inside porous materials called metal organic… Continue reading Super-porous material transports cancer-killing CRISPR inside cells
In some forms of blindness, certain parts of the eye still work but damage to light-sensitive cells disrupts vision. Now, researchers at a company called Nanoscope have used gene therapy to bypass damaged cells and restore some level of vision to mice … Continue reading Gene therapy restores partial vision to totally blind mice
The 2020 Nobel Prize in Chemistry has been awarded to the two scientists who discovered and refined the CRISPR/Cas9 gene-editing tool. One of the most important scientific breakthroughs of the last decade, CRISPR allows for relatively simple editing of… Continue reading CRISPR gene-editing inventors awarded 2020 Nobel Prize in Chemistry
Researchers from the University of Chicago’s Marine Biological Laboratory have, for the first time, successfully gene edited a cephalopod. Using CRISPR-Cas9 technology, the research breakthrough will now allow scientists to conduct novel investigations… Continue reading Squid gene-edited using CRISPR for the first time
Scientists in Australia have made an exciting breakthrough in Alzheimer’s research, demonstrating what they describe as the first gene-therapy-based approach for treating advanced forms of the disease. Through experiments in mice, the team was able to show how activating a key enzyme in the brain can prevent the kind of memory loss associated with advanced forms of Alzheimer’s, and even reverse it.
Tags: Alzheimer’s Disease, Macquarie University, Dementia, Brain, gene therapy, Neurological, New Atlas Audio
Continue reading World-first gene therapy reverses Alzheimer’s memory loss in mice
The CRISPR-Cas9 gene editing system is an extremely powerful tool, but there are still a few kinks to iron out. One of the main problems is off-target edits, which can have serious consequences. Now, researchers have found a particular mutation of the … Continue reading New CRISPR enzyme mutation proves almost 100 times more precise
Vertex and CRISPR Therapeutics have presented new data from one of the first trials testing gene-editing therapy in human subjects. Fifteen months on from the first patient treatment, the highly experimental therapy is showing remarkable efficacy treat… Continue reading More early data revealed from landmark CRISPR gene editing human trial
Part of what makes cancer so deadly is its ability to rapidly spread to other parts of the body, leading doctors into a deadly game of Whack-A-Mole. Now, researchers at Tulane University have identified a pair of genes that helps triple negative breast… Continue reading Blocking genes halts growth, spread of triple negative breast cancer
A compelling new study, led by scientists from Washington University School of Medicine in St. Louis, has found a novel gene therapy can prevent obesity and build muscle without the need for additional exercise, in mice being fed a high-fat diet.Contin… Continue reading Experimental gene therapy prevents obesity, builds muscle, without exercise or dieting