Trial drug shown to significantly slow early Alzheimer’s decline

The drug donanemab, which destroys the amyloid beta plaques that cause Alzheimer's disease, was the subject of a Phase 3 clinical trial

A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.

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Regular internet use by older adults linked to reduced dementia risk

A new long-term study by researchers at NYU has found that regular internet usage by older adults is linked with a decreased risk of dementia. But it’s about striking a balance, with evidence excessive use can be harmful to cognitive health.Continue Re… Continue reading Regular internet use by older adults linked to reduced dementia risk

Alzheimer’s proteins beaten back by sleeping pill in small study

While the sleeping pill known as suvorexant knocked back Alzheimer's markers, the researches are quick to caution that more studies are needed to assess its long-term health effects

Thirty-eight people took part in a study to investigate the effects of a sleep medication on Alzheimer’s-related proteins in their cerebrospinal fluid. The pills showed promise in combating the substances that lead to the harmful tangles and plaques in the brain that contribute to the disease, but larger more comprehensive studies are needed to confirm the results.

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Tickling the ivories may improve age-related cognitive decline

As we age, our brains naturally atrophy, and we experience cognitive decline. New research suggests that listening to music or playing a musical instrument may improve cognitive functioning in healthy older people.Continue ReadingCategory: Health &… Continue reading Tickling the ivories may improve age-related cognitive decline

Clear chemical connection between physical activity and brain health

Scientists unlock key chemical mechanisms that link brain health with muscle use

The link between physical activity and brain health is not new, with many studies showing how exercise can boost function, from easing depression to staving off cognitive decline. Now, scientists have shown in cell studies that the connection may be more direct, which opens the door to more targeted physical therapies for brain health and potential treatment of neurodegenerative conditions.

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Protocol predicts Alzheimer’s 10 years in advance with 80% accuracy

The number of people with dementia is set to almost double every 20 years, according to Alzheimer's Disease International

In seeking a safe yet effective way to predict Alzheimer’s disease, researchers found a sugar molecule in the blood of affected patients. When combined with a simple memory test and genetic analysis, the research team was able to predict the onset of the condition up to a decade in advance with a significant degree of accuracy. The protocol could soon join others in helping scientists spot Alzheimer’s in advance of its symptoms and take steps to halt its progression.

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World first reveals brain links between high blood pressure and dementia

Scientists get the clearest picture yet of how high blood pressure can trigger cognitive decline

For some time, scientists have known that high blood pressure is somehow involved in cognitive decline leading to dementia. Backing the evidence are several studies that saw blood pressure and related diabetes medicines help slow the loss of brain function.

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Calcium-control gene offers new avenue for Alzheimer’s disease therapy

Researchers have found the gene Surf4 plays a role in neural degeneration

Nearly six million Americans currently live with Alzheimer’s disease (AD), with the figure set to climb to 13.8 million by 2050. And with promising trials failing close to the finish line, researchers are desperate for any breakthroughs that will lead to halting the devastating neurodegenerative disease.

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