Dementia – Page 22 – WindowsTechs.com

Failed Alzheimer’s drugs given new life after human gene discovery

Posted on August 20, 2020 by Rich Haridy

The research suggests the presence of a key gene, only present in 75 percent of humans, could be the reason certain Alzheimer's drugs failed in clinical trials

A new study is questioning whether potential Alzheimer’s treatments previously found to be ineffective in human trials should be re-examined, after the discovery of a specific gene that can inhibit a therapy’s efficacy is only present in 75 percent of people.

Category: Science

Tags: Genetics, Alzheimer’s Disease, Dementia, Brain, Neuroscience, University at Buffalo

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Mucus shows promise as cheap and easy diagnostic tool for Alzheimer’s

Posted on August 12, 2020 by Nick Lavars

Alzheimer's researchers Professor Cheil Moon (left) and Gowoon Son (right) analyzing nasal discharge samples in the lab at Daegu Gyeongbuk Institute of Science and Technology

With so much we are yet to understand about how Alzheimer’s develops, scientists are coming at the problem from all kinds of angles. This includes exploring the disease’s relationship with our metabolism and our microbiome, and developing blood tests that could pick it up in its early stages. Scientists in South Korea have identified another pathway, and are reporting some promising results around an early diagnostic method that involves detecting biomarkers in nasal discharge.

Category: Medical, Science

Tags: Alzheimer’s Disease, Daegu Gyeongbuk Institute of Science and Technology, Neuroscience, Dementia, New Atlas Audio

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Imaging study offers clue to how obesity can increase Alzheimer’s risk

Posted on August 6, 2020 by Rich Haridy

A direct association between increased body weight and reduced blood flow in the brain was detected in a new study

New data from one of the largest brain imaging studies of its type has found a consistent association between increased body weight and decreased cerebral blood flow. The research offers greater insights into the links between Alzheimer’s and obesity, suggesting maintaining a healthy weight can directly reduce one’s risk of developing dementia.

Category: Health & Wellbeing, Lifestyle

Tags: Alzheimer’s Disease, Brain, Dementia, Neuroscience, Imaging, New Atlas Audio

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Anti-aging drug targets Alzheimer’s by altering metabolism in the brain

Posted on August 6, 2020 by Nick Lavars

Scientists studying the effects of an experimental drug in mice have uncovered new mechanisms that appear to drive the development of Alzheimer's

Scientists investigating Alzheimer’s treatments at the Salk Institute have uncovered some key mechanisms that enable an experimental drug to reverse memory loss in mouse models of the disease. The discovery not only bodes well for the possibility of clinical trials, but provides researchers with a new target to consider in the wider development of compounds to counter the degenerative effects of the condition.

Category: Medical, Science

Tags: Alzheimer’s Disease, Salk Institute, Neurological, Dementia, Brain, New Atlas Audio

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World-first gene therapy reverses Alzheimer’s memory loss in mice

Posted on July 30, 2020 by Nick Lavars

Research into Alzheimer's-related memory loss has uncovered an exciting new breakthrough in the form of a world-first gene therapy

Scientists in Australia have made an exciting breakthrough in Alzheimer’s research, demonstrating what they describe as the first gene-therapy-based approach for treating advanced forms of the disease. Through experiments in mice, the team was able to show how activating a key enzyme in the brain can prevent the kind of memory loss associated with advanced forms of Alzheimer’s, and even reverse it.

Category: Medical, Science

Tags: Alzheimer’s Disease, Macquarie University, Dementia, Brain, gene therapy, Neurological, New Atlas Audio

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Alzheimer’s blood test detects early toxic proteins with 86% accuracy

Posted on July 29, 2020 by Nick Lavars

A new blood test could one day aid in the early diagnosis of Alzheimer's

Alzheimer’s is a disease that can take hold in the brain long before symptoms, like memory and cognitive decline, become evident. This makes it a very tricky one to diagnose early in the piece, but a new breed of blood tests are emerging that could change the game in this regard. The latest centers on a new biomarker in the blood, which was shown to distinguish healthy patients from early asymptomatic Alzheimer’s patients with a high degree of accuracy.

Category: Medical, Science

Tags: Alzheimer’s Disease, Washington State University, Lund University, Dementia, Neurological

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Low suicide rates linked to microdoses of lithium in drinking water

Posted on July 28, 2020 by Rich Haridy

A new systematic review of more than a dozen studies from around the world has confirmed an association between geographical areas with naturally high levels of lithium in the water supply and low rates of suicide. The researchers suggest trials should… Continue reading Low suicide rates linked to microdoses of lithium in drinking water→

How Viagra is directing scientists toward a new Alzheimer’s treatment

Posted on July 27, 2020 by Rich Haridy

New research into erectile dysfunction drugs has uncovered a novel brain mechanism that could be pharmacologically targeted to help prevent neurodegenerative disease

A new study, from scientists at Harvard Medical School and the University of Cambridge, has described how drugs traditionally developed to treat erectile dysfunction may also improve the brain’s ability to clear toxic misfolded proteins linked with neurodegenerative diseases such as Alzheimer’s and Parkinson’s.

Category: Science

Tags: Viagra, Alzheimer’s Disease, Dementia, Protein, Neuroscience, Brain, New Atlas Audio

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Metastudy homes in on 10 strongest risk factors for Alzheimer’s disease

Posted on July 22, 2020 by Rich Haridy

Ten risk factors, including head trauma, obesity in latelife, and diabetes, have been identified as the strongest risk factors for Alzheimer's in a new study

A massive systematic review encompassing hundreds of clinical trials and observational studies has zeroed in on the 10 most common risk factors for Alzheimer’s disease. The researchers suggest avoiding these 10 factors could play a significant role in preventing the onset of Alzheimer’s.

Category: Health & Wellbeing, Lifestyle

Tags: Alzheimer’s Disease, Dementia, metabolism, Neuroscience

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Gene study suggests healthy aging linked to blood iron levels

Posted on July 17, 2020 by Rich Haridy

New research suggests the genes linked to healthy aging also play a role in iron metabolism

A large gene study has discovered several genomic regions linked to longer and healthier lives are also involved in metabolizing iron in the blood. The research suggests abnormal blood iron levels may fundamentally underpin many age-related diseases.

Category: Health & Wellbeing, Lifestyle

Tags: Aging, Lifespan, Blood, Dementia, Alzheimer’s Disease, Max Planck Institute, University of Edinburgh

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