Existing drug boots out ‘sleeping’ bone cells to relieve lower back pain

In some heartening news for the 80% of Americans who will endure lower back pain in their lifetime, researchers have found that an existing drug can be redeployed to target ‘sleeping’, or senescent, osteoclast cells to significantly reduce spinal hyper… Continue reading Existing drug boots out ‘sleeping’ bone cells to relieve lower back pain

“Off-the-shelf” cancer immunotherapy inches closer with new mouse study

Immunotherapy is a promising cancer treatment, but it can take too long to administer. In a new study, scientists at UCLA have taken steps towards an “off-the-shelf” therapy that could be mass produced and quickly rolled out to patients with a variety … Continue reading “Off-the-shelf” cancer immunotherapy inches closer with new mouse study

The first true chimeric monkey is born ‘glowing’ with two sets of DNA

In what sounds a little like the opening scenes from a sci-fi horror film, a team of scientists has taken seven-day-old monkey embryo stem cells and injected them into an unrelated four-to-five-day embryo from the same species, which was then injected … Continue reading The first true chimeric monkey is born ‘glowing’ with two sets of DNA

Drug found to reverse mitochondria malfunction & mitigate heart failure

Researchers have discovered a previously unknown pathological cellular mechanism underpinning heart failure, which currently has no cure, and identified a drug that can reverse the damaging malfunction. The findings open the door to a novel interventio… Continue reading Drug found to reverse mitochondria malfunction & mitigate heart failure

Promising cancer drug may effectively treat gout and heart disease

There are a lot of research eyes on the development of Polo-like kinase 1 (PLK1) inhibitors for cancer treatment right now, with several drugs currently in clinical trials and at least one in late-stage Phase III testing. But University of Cambridge sc… Continue reading Promising cancer drug may effectively treat gout and heart disease

First look at a mechanism cancer cells use to resist chemotherapy

Researchers have, for the first time, observed a mechanism used by cancer cells to resist the effects of chemotherapy. The findings could be used to develop targeted drugs to help override it and make chemotherapy more effective.Continue ReadingCategor… Continue reading First look at a mechanism cancer cells use to resist chemotherapy

Implanting insulin-producing cells into the eye could help treat diabetes

Diabetes is one of the most pressing health concerns of our time, and now Swedish scientists have demonstrated a new potential way to manage the disease. It turns out the eye might be a useful place to implant insulin-producing cells to control blood s… Continue reading Implanting insulin-producing cells into the eye could help treat diabetes

Converting brain immune cells into neurons aids post-stroke recovery

Researchers have converted brain immune cells into neurons, replacing damaged ones and restoring function in stroke-affected mice. The next step is to see if the same results can be achieved using human brain cells, opening the door to a potential trea… Continue reading Converting brain immune cells into neurons aids post-stroke recovery

Thousands of Fanzor DNA cutters that may outperform CRISPR identified

Following on from the discovery of programmable DNA-cutting enzymes known as Fanzors, scientists have found that a diverse range of species possess these genetic ‘scissors’, which presents a massive opportunity in the development of new medicines, gene… Continue reading Thousands of Fanzor DNA cutters that may outperform CRISPR identified

New two-in-one microscope gives a detailed glimpse inside cells

Researchers have combined two microscopic imaging techniques in one microscope, providing scientists with a high-resolution method of tracking single molecules in a cellular context. The development opens the door to improving our ability to visualize,… Continue reading New two-in-one microscope gives a detailed glimpse inside cells