Alzheimer’s Disease – Page 25

Women develop Alzheimer’s more than men due to hormones, suggests study

Posted on June 25, 2020 by Rich Haridy

New brain imaging research suggests a drop in estrogen levels following menopause may accelerate the progression of Alzheimer's in those already predisposed to the disease

A detailed new brain imaging study, examining a number of cognitively healthy middle-aged subjects, is suggesting lower levels of estrogen in women post-menopause could play a role in triggering brain changes linked to Alzheimer’s disease. The research hypothesizes this mechanism may be one of the reasons why women suffer from Alzheimer’s at greater rates than men.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Brain, Medical Imaging, Neuroscience, fMRI

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Switching off noisy neurons in mice restores memories lost to Alzheimer’s

Posted on June 10, 2020 by Michael Irving

A new mechanism by which Alzheimer's impairs memory recall has been discovered

Researchers in Germany have discovered a new mechanism by which Alzheimer’s disease impairs memory recall – and, importantly, found a way to reverse it in mice. Neurons encoded with existing memories are being drowned out by noise from neurons encoding new experiences, and silencing these allowed the mice to regain lost memories.

Category: Medical, Science

Tags: Alzheimer’s Disease, DZNE, Brain, Neuroscience, Memory

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Positive early Alzheimer’s trial results for repurposed cancer drug

Posted on June 3, 2020 by Rich Haridy

A drug originally developed to treat leukemia, and approved for use in the United States in 2007, has shown promise for treating Alzheimer's

Encouraging results from a small Phase 2 human trial testing the effects of a cancer drug in treating Alzheimer’s disease have been published in the journal Annals of Neurology. The data suggests the drug is safe, well-tolerated and alters biomarkers associated with Alzheimer’s. A larger efficacy study is currently planned.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Brain, Protein, Parkinson’s Disease, Georgetown University

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Biomarker detects Alzheimer’s decades before symptoms appear

Posted on June 1, 2020 by Rich Haridy

A protein released into the body as a result of neuronal damage could indicate the early stages of neurodegenerative diseases such as Alzheimer's and Huntington's over 20 years before symptoms appear

Two new studies, published in the journal The Lancet Neurology, are suggesting increasing levels of a particular brain protein, detected in blood and spinal fluid, could be the earliest sign of neurodegenerative diseases such as Alzheimer’s and Huntington’s.

Category: Medical, Science

Tags: Alzheimer’s Disease, Neuroscience, Dementia, Brain, Diagnosis, University College London, Massachusetts General Hospital, New Atlas Audio

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Biomarker detects Alzheimer’s decades before symptoms appear

Posted on June 1, 2020 by Rich Haridy

A protein released into the body as a result of neuronal damage could indicate the early stages of neurodegenerative diseases such as Alzheimer's and Huntington's over 20 years before symptoms appear

Category: Medical, Science

Tags: Alzheimer’s Disease, Neuroscience, Dementia, Brain, Diagnosis, University College London, Massachusetts General Hospital, New Atlas Audio

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Antibody breakthrough promises new view of toxic Alzheimer’s proteins

Posted on May 26, 2020 by Rich Haridy

Researchers have not had an accurate or easy way to detect amyloid oligomers, the protein accumulations smaller than the commonly known plaques – until now

An international team of scientists has designed a novel antibody that can accurately detect the toxic oligomers suspected to cause the neurodegeneration associated with Alzheimer’s disease. It’s hoped the breakthrough will lead to improved drug design and clinical testing by offering researchers a new way to measure these protein aggregations.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Protein, antibodies, University of Cambridge, Neuroscience, New Atlas Audio

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Aerobic exercise shown to improve memory in those at risk of dementia

Posted on May 25, 2020 by Rich Haridy

A 12-month study found aerobic exercise improves blood flow to parts of the brain linked with memory

The results of a year-long trial led by researchers at UT Southwestern have homed in on how aerobic exercise can improve memory in older subjects with mild cognitive impairment. The findings suggest it is never too late to start exercising as aerobic activity improves blood flow to regions of the brain associated with memory.

Category: Health & Wellbeing, Lifestyle

Tags: Alzheimer’s Disease, Dementia, Exercise, Brain, Neurological, UT Southwestern, New Atlas Audio

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DNA-repairing enzyme reverses age-related cognitive decline

Posted on May 20, 2020 by Michael Irving

Researchers have shown that an enzyme called HDAC1 helps repair DNA damage and fight off age-related cognitive decline

DNA damage is common to our cells, but when we’re young our bodies can fix it pretty easily. Unfortunately we lose that ability over time, leading to many of the symptoms of aging that we know all too well. A new study from MIT has found that reactivating a certain enzyme improves repair of DNA damage in neurons, which helps Alzheimer’s patients and others with cognitive decline.

Category: Medical, Science

Tags: Brain, Neuroscience, MIT, Alzheimer’s Disease, Enzyme, Aging, New Atlas Audio

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Elevated calcium in mitochondria linked to cell death in Alzheimer’s

Posted on May 13, 2020 by Nick Lavars

A new study has uncovered a relationship between elevated levels of calcium ions in the mitochondria and cell death in Alzheimer's

There are many unknowns when it comes to the complex mechanisms underpinning Alzheimer’s disease, but research is continuing to shine a light on some of the key suspects. A new mouse study from Massachusetts General Hospital has for the first time established a connection between elevated levels of calcium in mitochondria and neuron death associated with the disease, offering a potential new target for efforts to slow its progression.

Category: Medical, Science

Tags: Alzheimer’s Disease, Massachusetts General Hospital, Brain, Dementia, Neuroscience

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New compound combats the metal ions and plaques linked to Alzheimer’s

Posted on May 8, 2020 by Nick Lavars

A newly developed compound could attack various facets of Alzheimer's disease

While its exact causes are unknown, Alzheimer’s disease is commonly associated with clumps of toxic amyloid plaques in the brain, and researchers are continuing to understand the different components that help them take shape. Scientists at the University of Illinois at Urbana-Champaign have developed a new compound that attacks a number of the key players in the formation of amyloid plaques, significantly decreasing the level of plaques and reducing inflammation in the brain.

Category: Medical, Science

Tags: Alzheimer’s Disease, University of Illinois, Dementia, Brain, New Atlas Audio

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