Researchers discover new way fat cells talk directly with the brain

An incredible new study led by a team from the Scripps Research Institute has discovered a novel communication pathway between fat cells and the brain. The findings reveal that the brain doesn’t regulate fat burning by just slowly responding to hormona… Continue reading Researchers discover new way fat cells talk directly with the brain

Newly discovered chemical reactions could explain the origin of life

Exactly how non-living molecules sparked into life is one of the most puzzling mysteries of science. Now scientists at Scripps Research have discovered a new set of chemical reactions that can produce the building blocks of life out of materials though… Continue reading Newly discovered chemical reactions could explain the origin of life

Newly discovered chemical reactions could explain the origin of life

Exactly how non-living molecules sparked into life is one of the most puzzling mysteries of science. Now scientists at Scripps Research have discovered a new set of chemical reactions that can produce the building blocks of life out of materials though… Continue reading Newly discovered chemical reactions could explain the origin of life

Discovery of mechanical itch protein hints at new treatments for eczema

Scientists investigating the cellular basis for itching have made an important discovery, and one that could lead to new treatments of chronic conditions like eczema. The breakthrough centers on what’s known as mechanical itching, with the research tea… Continue reading Discovery of mechanical itch protein hints at new treatments for eczema

Protein linked to alcoholism relapse offers novel target for treatment

Alcohol use disorder is a leading cause of preventable death and a complex disease, but by understanding its effects on brain function scientists hope to lower the risk and rates of relapse. The latest finding in this space comes from Scripps Research … Continue reading Protein linked to alcoholism relapse offers novel target for treatment

Smartphone app calculates your genetic risk for heart disease

A new smartphone app called MyGeneRank has been developed by scientists at the Scripps Research Translational Institute. The app calculates a person’s genetic risk for coronary artery disease and directs those found to be at high risk to appropriate me… Continue reading Smartphone app calculates your genetic risk for heart disease

Blocking metabolic effects of obesity potentially prevents diabetes

Scientists at the Scripps Research Institute have spent the past few years studying a promising but problematic signaling pathway they believe can be targeted to prevent type 2 diabetes. The team has now demonstrated how this pathway can be temporarily… Continue reading Blocking metabolic effects of obesity potentially prevents diabetes

Can Alzheimer’s be tackled by cutting cholesterol in the brain?

Scientists have uncovered a mechanism that may allow Alzheimer's to be tackled by controlling cholesterol levels in the brain

One interesting area of Alzheimer’s research focuses on the relationship between cholesterol in the brain and onset of the disease, with studies suggesting the compound can greatly accelerate the buildup of troublesome brain plaques. A new study has expanded our knowledge of this phenomenon by observing it in action in live mice, with the scientists even finding they could intervene in cholesterol production to make the plaques all but disappear.

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Continue reading Can Alzheimer’s be tackled by cutting cholesterol in the brain?

“Undruggable” cancer protein targeted by compound from shrub root

Scientists at Purdue University and the Scripps Research Institute have identified a natural compound from a common shrub that could help fight cancer. The compound is the first found to inhibit a cancer protein that was previously considered “undrugga… Continue reading “Undruggable” cancer protein targeted by compound from shrub root