Collaborate Disseminate
Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune responses. Importantly, they’ve also discovered a so… Continue reading mRNA mod responsible for off-target effects identified & fixed
Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.
Tags: Medical Research Council, Dementia, Alzheimer’s Disease, Protein, Brain, Neuroscience, Neurological
Continue reading Rogue protein linked to early-onset dementia identified
A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeu… Continue reading Protein discovery raises prospect of treatment for COPD
A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeu… Continue reading Protein discovery raises prospect of treatment for COPD
Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue. The discovery not only improves our understanding of the metastatic process but is the first step to d… Continue reading Protein discovery could be used to stop breast cancer in its tracks
Researchers have identified cell-specific proteins in eye fluid and used AI to determine which proteins accelerated aging in particular diseases. Understanding the cellular origin of these disease-driving proteins may lead to precision treatments and m… Continue reading Technique that determines ‘eye age’ could lead to precision treatments
A new study has found that light therapy applied to mice during deep sleep increased the brain’s ability to clear away beta-amyloid, a toxic protein linked to the development of Alzheimer’s disease. The finding may lead to a non-drug, non-invasive treatment for the condition.
Tags: Light, Alzheimer’s Disease, Protein, Brain
Continue reading Light therapy helps the brain clear out toxic Alzheimer’s proteins
Researchers have identified how the SARS-CoV-2 virus that causes COVID-19 takes advantage of our cellular machinery to replicate and spread in the body, and, importantly, a way to stop it. The finding could lead to the development of a new class of ant… Continue reading COVID’s – and other viruses’ – Achilles’ heel identified
Researchers have identified a protein that’s critical to the development of skeletal muscle mass and strength and the tissue’s ability to metabolize glucose. They say their findings may lead to treatments for the muscle wasting that can occur in diseas… Continue reading Protein linked to muscle development could be new atrophy treatment target
A new study has revealed how the mutated proteins that are a hallmark of Parkinson’s disease spread and aggregate in the brain. The finding opens the door to developing a way of halting the disease’s progression and may be useful in tackling other neurodegenerative diseases caused by protein aggregation.
Tags: Parkinson’s Disease, Protein, Neurological
Continue reading Study reveals how mutated protein invades the brain in Parkinson’s