Protein – Page 2 – WindowsTechs.com

“Chemical chaperone” improves Alzheimer’s signs in early & late disease

Posted on December 21, 2023 by Paul McClure

Treatment with a supplementary 'chemical chaperone' has been shown to reduce protein plaques and improve cognitive performance in Alzheimer's disease

A new study has found that treatment with a ‘chemical chaperone’ assists in reducing the accumulation of protein plaques and restores cognitive functioning in mouse models of Alzheimer’s disease. The findings could lead to novel treatments to help treat this debilitating disease.

Category: Medical, Science

Tags: Alzheimer’s Disease, Protein, Brain, University of Pennsylvania

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mRNA mod responsible for off-target effects identified & fixed

Posted on December 8, 2023 by Paul McClure

Researchers have discovered that a chemical modification to the synthetic messenger RNA used in therapeutics can cause the cell’s machinery to misread its instructions and result in unintended immune responses. Importantly, they’ve also discovered a so… Continue reading mRNA mod responsible for off-target effects identified & fixed→

Rogue protein linked to early-onset dementia identified

Posted on December 8, 2023 by Bronwyn Thompson

A visualization of the structure of TAF15 amyloid filaments (in yellow), as detected by cryo-EM in the brains of four dementia patients

Scientists have identified odd clusters of a specific protein in the brains of people with early-onset dementia, pointing to a potential cause, a diagnostic tool and, ultimately, a therapy target for a disease that’s been largely a mystery to researchers.

Category: Medical, Science

Tags: Medical Research Council, Dementia, Alzheimer’s Disease, Protein, Brain, Neuroscience, Neurological

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Protein discovery raises prospect of treatment for COPD

Posted on November 16, 2023 by Paul McClure

A new study has found that TLR7, a protein that normally triggers our immune system to defend against certain viruses, plays a pivotal role in exacerbating chronic obstructive pulmonary disease or COPD. The unexpected discovery may lead to new therapeu… Continue reading Protein discovery raises prospect of treatment for COPD→

Protein discovery raises prospect of treatment for COPD

Posted on November 16, 2023 by Paul McClure

Protein discovery could be used to stop breast cancer in its tracks

Posted on October 30, 2023 by Paul McClure

Researchers have uncovered the mechanism by which a protein facilitates the spread of breast cancer cells from the primary tumor into healthy tissue. The discovery not only improves our understanding of the metastatic process but is the first step to d… Continue reading Protein discovery could be used to stop breast cancer in its tracks→

Technique that determines ‘eye age’ could lead to precision treatments

Posted on October 20, 2023 by Paul McClure

Researchers have identified cell-specific proteins in eye fluid and used AI to determine which proteins accelerated aging in particular diseases. Understanding the cellular origin of these disease-driving proteins may lead to precision treatments and m… Continue reading Technique that determines ‘eye age’ could lead to precision treatments→

Light therapy helps the brain clear out toxic Alzheimer’s proteins

Posted on September 25, 2023 by Paul McClure

A study has found that light therapy during sleep could help the brain's lymphatic system clear away the beta-amyloid proteins associated with Alzheimer's disease

A new study has found that light therapy applied to mice during deep sleep increased the brain’s ability to clear away beta-amyloid, a toxic protein linked to the development of Alzheimer’s disease. The finding may lead to a non-drug, non-invasive treatment for the condition.

Category: Medical, Science

Tags: Light, Alzheimer’s Disease, Protein, Brain

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COVID’s – and other viruses’ – Achilles’ heel identified

Posted on September 15, 2023 by Paul McClure

Researchers have identified how the SARS-CoV-2 virus that causes COVID-19 takes advantage of our cellular machinery to replicate and spread in the body, and, importantly, a way to stop it. The finding could lead to the development of a new class of ant… Continue reading COVID’s – and other viruses’ – Achilles’ heel identified→

Protein linked to muscle development could be new atrophy treatment target

Posted on September 11, 2023 by Paul McClure

Researchers have identified a protein that’s critical to the development of skeletal muscle mass and strength and the tissue’s ability to metabolize glucose. They say their findings may lead to treatments for the muscle wasting that can occur in diseas… Continue reading Protein linked to muscle development could be new atrophy treatment target→