Tag Archives: Protein

Positive early Alzheimer’s trial results for repurposed cancer drug

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A drug originally developed to treat leukemia, and approved for use in the United States in 2007, has shown promise for treating Alzheimer's

Encouraging results from a small Phase 2 human trial testing the effects of a cancer drug in treating Alzheimer’s disease have been published in the journal Annals of Neurology. The data suggests the drug is safe, well-tolerated and alters biomarkers associated with Alzheimer’s. A larger efficacy study is currently planned.

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Scientists identify two protein pieces of the cancer puzzle

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How cancer develops is a complex puzzle, involving untold moving parts and chemical reactions. Now, scientists have found how two of these pieces work together to prevent cancer forming, which could unlock new types of cancer treatments.Continue Readin… Continue reading Scientists identify two protein pieces of the cancer puzzle→

Antibody breakthrough promises new view of toxic Alzheimer’s proteins

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Researchers have not had an accurate or easy way to detect amyloid oligomers, the protein accumulations smaller than the commonly known plaques – until now

An international team of scientists has designed a novel antibody that can accurately detect the toxic oligomers suspected to cause the neurodegeneration associated with Alzheimer’s disease. It’s hoped the breakthrough will lead to improved drug design and clinical testing by offering researchers a new way to measure these protein aggregations.

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Bacterial attack system hijacked and controlled with light

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Some bacteria are known to inject toxins into host cells using a syringe-like appendage. Past research has found that we might be able to hijack that as a new drug delivery system, and now scientists from the Max Planck Institute have developed a way t… Continue reading Bacterial attack system hijacked and controlled with light→

Cell-division helper protein identified as potential cancer target

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Cell division is a crucial process in the body, but cancer cranks it into overdrive with often deadly results. Now, researchers from the University of Copenhagen have identified a protein that plays a key role in the process, meaning it could be a futu… Continue reading Cell-division helper protein identified as potential cancer target→

“Peptide pills” breakthrough could open new avenue for oral drugs

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Peptides do important work, and could be a largely untapped type of drug. The problem is they can’t be taken orally, because stomach acids destroy them before they can get into the bloodstream. Now, researchers at EPFL have developed a new method of te… Continue reading “Peptide pills” breakthrough could open new avenue for oral drugs→

Potentially exploitable weakness found in bacteria’s outer armor

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For bacteria, the first line of defense is the cell wall, which keeps toxins such as antibiotics out. Now, researchers have discovered a key mechanism that bacteria use to build their cell walls, which could present a new target in the ongoing quest to… Continue reading Potentially exploitable weakness found in bacteria’s outer armor→

Scientists turn the tables on cancer with new immunotherapy target

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One of the best weapons against cancer might have been inside us all along – our own immune systems. Immunotherapy involves supercharging the immune system to better root out cancer from its hiding places, and now researchers at EPFL have discovered a … Continue reading Scientists turn the tables on cancer with new immunotherapy target→

Flipping a protein switch could help hearts heal after an attack

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The human body is good at replenishing cells to repair damage, but one vital organ lacks this ability – the heart. But now, researchers at the University of Texas Southwestern Medical Center have uncovered a suite of proteins in mice that could be swit… Continue reading Flipping a protein switch could help hearts heal after an attack→

Novel antibody treatment proposed for obsessive compulsive disorder

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A new study has described the accidental discovery of a novel protein that may be associated with the anxiety and stress behaviors seen in obsessive compulsive disorder (OCD). Blocking the expression of this protein in mice reduced anxious behaviors, o… Continue reading Novel antibody treatment proposed for obsessive compulsive disorder→