Stimulation of brain’s “depression switch” offers rapid, sustained relief

The past decade of research into deep brain stimulation (DBS), in which implanted electrodes are used to target specific brain regions with electrical impulses, has brought to light its potential to tackle a variety of neurological disorders. Depressio… Continue reading Stimulation of brain’s “depression switch” offers rapid, sustained relief

Newly discovered biomarker predicts COVID-19 death days in advance

Researchers from The Mount Sinai Hospital have found changes to electrical activity in the heart can help predict which hospitalized COVID-19 patients are more likely to decline and die. The biomarker is easily measurable and potentially predicts death… Continue reading Newly discovered biomarker predicts COVID-19 death days in advance

Psychedelic research center launched at New York’s Mount Sinai

Surfing the wave of novel research into medical uses for psychedelic compounds, the Icahn School of Medicine at Mount Sinai has launched a dedicated psychedelic center focusing initially on the study of MDMA and psilocybin for PTSD and other stress-rel… Continue reading Psychedelic research center launched at New York’s Mount Sinai

Alzheimer’s brain tissue study uncovers three distinct disease subtypes

Researchers analyzed more than 1,500 postmortem brain tissue samples to distinguish the molecular differences between various cases of Alzheimer's disease

Despite decades of rigorous research, scientists are still struggling to crack the mystery of Alzheimer’s disease. Promising preclinical research has consistently led to frustrating clinical trial failures and some have started to question whether we are even targeting the correct pathological mechanisms.

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Continue reading Alzheimer’s brain tissue study uncovers three distinct disease subtypes

Phase 1 human trial for universal flu vaccine reports promising results

Even after decades of research and expansive global vaccination strategies, seasonal influenza still kills hundreds of thousands of people every year. The virus’s ability to mutate and evade our vaccines means we are constantly chasing the latest strai… Continue reading Phase 1 human trial for universal flu vaccine reports promising results

Experimental drug halves cholesterol levels in phase 2 clinical trials

Scientists are reporting promising results from a phase 2 clinical trial of a cholesterol-reducing drug called evinacumab. The study reports that in patients with extremely high cholesterol, the drug was able to reduce levels by about half, compared to… Continue reading Experimental drug halves cholesterol levels in phase 2 clinical trials

Signs of metal in teeth could indicate ALS risk from childhood

A compelling new study is suggesting signs of the neurodegenerative disease Amyotrophic lateral sclerosis (ALS) may be detectable in teeth, decades before the onset of any symptoms. The research points to a lifelong dysfunction in metabolizing metals a… Continue reading Signs of metal in teeth could indicate ALS risk from childhood