A stomach virus is suspected to trigger inflammatory bowel disease

New research led by a team from New York University has found evidence a common viral infection can trigger inflammatory bowel disease in genetically susceptible people. Across a series of mouse experiments the researchers demonstrated how a norovirus … Continue reading A stomach virus is suspected to trigger inflammatory bowel disease

Air pollution study upends basic ideas for how cancer develops

Extraordinary new research led by scientists from the Francis Crick Institute presents a new hypothesis as to how cancer develops. Inspired by a forgotten body of study from 75 years ago, the research looked at how air pollution drives the development … Continue reading Air pollution study upends basic ideas for how cancer develops

Rheumatoid arthritis protein discovery points to potential new therapy

A team of researchers in the United States has discovered a novel mechanism in which a key protein drives the inflammatory damage associated with rheumatoid arthritis. The foundational finding is hoped to direct research toward entirely new pathways to… Continue reading Rheumatoid arthritis protein discovery points to potential new therapy

New rheumatoid arthritis drug passes Phase 3 trial, looks to approval

Research published in The New England Journal of Medicine has reported positive Phase 3 trial results for a new monoclonal antibody treatment targeting rheumatoid arthritis. The novel therapy is hoped to offer a new option for patients struggling with … Continue reading New rheumatoid arthritis drug passes Phase 3 trial, looks to approval

Bedside AI warning system for sepsis reduces mortality by nearly 20%

Infections can trigger all kinds of reactions in the human body, and one of the most extreme is sepsis. This life-threatening complication causes more than 250,000 deaths in the US each year, but a new artificial intelligence system developed at Johns … Continue reading Bedside AI warning system for sepsis reduces mortality by nearly 20%

Brain inflammation links sleep disruption and Alzheimer’s

A new study has found inflammatory biomarkers correlated with disruptions to fast sleep spindles, a kind of sleep brain wave activity linked to memory retention

A new study suggests brain inflammation is the key factor linking sleep disturbances with Alzheimer’s disease. It’s hypothesized the same overactive immune cells in the brain that ultimately contribute to cognitive decline can disrupt certain sleep cycles in the earliest stages of neurodegenerative disease.

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Another study ties Alzheimer’s progression to bacteria in your mouth

Researchers have found mice infected with a certain type of oral bacteria displayed faster progression of Alzheimer's symptoms compared to uninfected animals

A common type of oral bacteria associated with periodontal disease has been linked to neuroinflammation and the progression of Alzheimer’s disease. The research, from an international team of scientists, builds on a prior body of evidence linking poor oral health with dementia and neurodegeneration.

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COVID-19 increases risk of Alzheimer’s, Parkinson’s & stroke, study finds

Looking at millions of health records in Denmark across 2020 and 2021, researchers saw higher rates of several neurodegenerative diseases in patients following COVID-19 infections

New research presented recently at the European Academy of Neurology Congress in Vienna has found an increased risk of several neurological disorders in patients following a bout of COVID-19. The study found the risk of Alzheimer’s, Parkinson’s and stroke all increased in COVID-positive subjects compared to those uninfected.

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Existing cancer drug suppresses inflammation behind multiple sclerosis

Reducing brain inflammation associated with multiple sclerosis is a key aim for researchers

The search for the root cause of neurodegenerative diseases like multiple sclerosis (MS) has turned up many suspects, but one central to many research efforts is a type of immune cell called microglia. The dysfunction of these key cogs in the central nervous system has prompted a wide-ranging search for drugs that can alter their activity, but new research suggests we might already have one such drug at our disposal, with an existing drug delivering significant therapeutic effects on experimental models of MS.

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Cross-talking neurons spill secrets of inflammation spread in arthritis

As the underlying cause of rheumatoid arthritis and other autoimmune disorders, there is considerable interest in deepening our understanding of chronic inflammation and the way it takes hold in the human body. Shedding new light on this is a new study… Continue reading Cross-talking neurons spill secrets of inflammation spread in arthritis