Ultrasound guides supercharged immune cells to only attack cancer

CAR T cell therapy is a promising new potential treatment for cancer, but it can trigger dangerous side effects in healthy tissue. Now, researchers at the University of California San Diego have found a way to focus the treatment more precisely, by eng… Continue reading Ultrasound guides supercharged immune cells to only attack cancer

Triple-combo of drugs targeting pancreatic cancer looks to human trials

Impressive new preclinical work from a team at MIT has found a combination of three experimental immunotherapy drugs could help shrink, or even eliminate, pancreatic tumors. Each of the three drugs have demonstrated safety in early-stage human trials a… Continue reading Triple-combo of drugs targeting pancreatic cancer looks to human trials

Tool that calculates immune system age could predict frailty and disease

New research from the Stanford University School of Medicine and the Buck Institute for Research on Aging is demonstrating a new tool that can calculate a person’s immune system age. The findings suggest tracking the degree of low-grade chronic inflamm… Continue reading Tool that calculates immune system age could predict frailty and disease

Understanding “marathon” cells key to waking up exhausted immune system

An impressive new study from a team of Australian researchers has identified the novel mechanism behind immune exhaustion. The findings point to a treatment method that could improve the success of cancer immunotherapy and help patients beat back sever… Continue reading Understanding “marathon” cells key to waking up exhausted immune system

Microbiome metabolites may boost cancer immunotherapy effectiveness

It’s hard to overstate the incredible influence our gut microbiome has on our health. Now, researchers have found that certain metabolites from intestinal bacteria could boost the cancer-killing effect of immunotherapy.Continue ReadingCategory: Medical… Continue reading Microbiome metabolites may boost cancer immunotherapy effectiveness

Cancer immunotherapy breakthrough reactivates tumor suppressor protein

Researchers at Karolinska Institute in Sweden have made a breakthrough in the arms race that is cancer immunotherapy. The team has blocked a protein that silences an important tumor-suppressing protein, allowing the latter to get back to work.Continue … Continue reading Cancer immunotherapy breakthrough reactivates tumor suppressor protein

New CAR-NK cell immunotherapy safely tackles breast cancers in lab tests

Immunotherapy is a promising avenue for cancer treatment, but it has trouble against solid tumors without triggering major side effects. Now, researchers at McMaster University have developed a new form of the treatment that supercharges a different ty… Continue reading New CAR-NK cell immunotherapy safely tackles breast cancers in lab tests

Type 1 diabetes vaccine effective in patients with specific gene variant

Results from a Phase 2 trial testing a novel type 1 diabetes vaccine have found the treatment is effective in a patient subgroup with a specific genetic variant. If validated in larger trials the new treatment could be helpful in around 50 percent of p… Continue reading Type 1 diabetes vaccine effective in patients with specific gene variant

Cancer vaccine and immunotherapy team up against tumors

Cancer treatments have long been limited to things like chemotherapy and radiation therapy, but in recent years more effective methods are emerging. Now, scientists at the University of Konstanz have found that combining two experimental methods – a va… Continue reading Cancer vaccine and immunotherapy team up against tumors

New immunotherapy double-crosses cancer to kill it from within

One of cancer’s crafty tricks involves manipulating the host’s immune cells to protect the tumors instead of fighting them. But now, researchers at Massachusetts General Hospital (MGH) have turned the tables around again, transforming these cells back … Continue reading New immunotherapy double-crosses cancer to kill it from within