Collaborate Disseminate
Migraine and glucose-related traits such as fasting insulin and type 2 diabetes are widely understood to be common comorbid disorders, but now scientists have a concrete genetic link that could see a new area of therapy developed for the debilitating d… Continue reading Genetic link between migraine and blood sugar levels confirmed
Amyotrophic lateral sclerosis (ALS) is a debilitating neurodegenerative disease with poor outcomes, but a pair of new studies may point towards a more optimistic future. In tests in human cells and live mice, the scientists identified a gene and a prot… Continue reading Scientists discover two new potential avenues of treatment for ALS
Researchers studying the hearts of healthy centenarians have homed in on a specific genetic mutation that seems to play a crucial role in maintaining cardiovascular functions in old age. Across a series of lab and animal experiments the researchers dem… Continue reading Unique gene mutation in superagers could rewind heart age by a decade
Scientists at Harvard Medical School have investigated why we age, and identified a possible way to reverse it. In tests in mice, the team showed that epigenetic “software glitches” drive the symptoms of aging – and a system reboot can reverse them, po… Continue reading Epigenetic “reboot” reverses aging in mice and could extend lifespan
Science is often a piecemeal process, progressing slowly through the incremental accumulation of knowledge. In the world of medical science this is particularly evident as small targeted research findings one year may, or may not, lead to massive life-… Continue reading The biggest medical milestones of 2022
A rare genetic disease that renders children without a functioning immune system from birth has been effectively cured by an experimental gene therapy. A new study is reporting on the first 10 children treated with the therapy, all of whom are now heal… Continue reading Gene therapy cures kids with rare “bubble-boy” disease in new trial
A Phase 3 trial testing the world’s first topical gene therapy has reported extraordinary results in children suffering from a rare blistering skin disease. The gene therapy gel was seen to completely heal wounds that had been open for years.Continue R… Continue reading World-first topical gene therapy gel heals decades-old wounds
A new technique has been added to the CRISPR gene-editing toolbox. Known as PASTE, the system uses virus enzymes to “drag-and-drop” large sections of DNA into a genome, which could help treat a range of genetic diseases.Continue ReadingCategory: Biolog… Continue reading New CRISPR gene-editing system can “drag-and-drop” DNA in bulk
The US Food and Drug Administration (FDA) has approved the first ever cell-based gene therapy, a one-off treatment for patients with a rare genetic blood disease. The single treatment will cost US$2.8 million, making it the most expensive medicine in h… Continue reading New $2.8-million gene therapy becomes most expensive medicine in history
Researchers at the Salk Institute have made a breakthrough that could lead to new treatments for genetic hearing loss. Gene therapy that delivers a particular protein can ensure faulty hair cells grow correctly, allowing for improved hearing.Continue R… Continue reading New gene therapy could prevent genetic hearing loss