Tag Archives: Dementia

Alzheimer’s trial supports high amyloid levels as early sign of disease

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An ongoing long-term trial suggests high levels of amyloid proteins in the brain do serve as an early sign of Alzheimer's disease before cognitive decline becomes apparent

A new study presenting the first data from a long-running US government trial is suggesting high levels of amyloid proteins in the brains of cognitively normal older adults can be an effective presymptomatic sign of early stage Alzheimer’s disease.

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Large study finds asprin does not reduce risk of developing Alzheimer’s

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A new study has found that daily consumption of aspirin offers no benefit when it comes to cognitive impairment associated with dementia and Alzheimer's

The idea that regular consumption of aspirin can reduce the symptoms of dementia has been the source of much contention in scientific circles. Researchers behind a new large-scale study involving almost 20,000 patients are the latest to weigh in on this debate, with their multi-year investigation uncovering no evidence of therapeutic benefit when it comes to staving off this Alzheimer’s and other types of cognitive impairment.

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How the brain’s immune cells both help and harm in cases of Alzheimer’s

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Microglia, the brain's immune cells, are being investigated for the role they may play in the progression of Alzheimer's disease

A trio of new studies are investigating the role our brain’s immune cells play in the progression of Alzheimer’s disease. Researchers are revealing how these immune cells can contribute to neurodegeneration, and how they may be harnessed to prevent neuron damage.

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Cambridge study adds evidence linking brain inflammation with dementia

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A new study has found a link between the build-up of damaging toxic proteins and the presence of neuroinflammation in three different types of dementia

A new imaging study has found neuroinflammation may be more common in neurodegenerative diseases than previously suspected. The Cambridge research revealed brain inflammation to be a common thread across three different types of dementia.

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Newly discovered mechanism links sleep regulation and Alzheimer’s

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A new study is the first link to sleep and neurodegeneration to the same signaling pathway in the brain

The link between diseases such as Alzheimer’s and sleep loss has been frequently cited by researchers, and a new study led by scientists from the University of Pennsylvania has discovered a signaling pathway that both regulates sleep and controls the protein aggregations commonly associated with neurodegeneration. It’s hoped the discovery will lead to better therapies to reduce the risk of Alzheimer’s and improve sleep quality.

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How bilingualism can hold back a flood of Alzheimer’s symptoms

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A new study has found that while bilingualism can hold back the symptoms of Alzheimer's disease, it can also lead to a faster decline down the track

A long line of research projects have found a range of benefits of bilingualism when it comes to the brain, from shortening recovery times from stroke to staving off the cognitive decline associated with dementia and Alzheimer’s. Scientists looking into the latter have uncovered some interesting new insights, finding that while knowing a second language can delay the onset of the disease, it can also significantly accelerate the deterioration into severe Alzheimer’s thereafter.

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Shoe with GPS embedded insole tracks ‘lost’ alzheimer’s & dementia patients

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By Uzair Amir
The shoe insole equipped with a built-in GPS tracker can also help you track your kids.
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New Alzheimer's hypothesis suggests cellular garbage disposal system could be key to prevention

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Research suggests toxic amyloid and tau proteins can change their molecular shape to avoid detection and ...

Researchers from the University of California, Riverside, have offered new evidence suggesting dysfunction in the lysosome system, our body’s cellular garbage disposal mechanism, could be the underlying cause of Alzheimer’s disease. The hypothesis is not entirely novel but the research describes a newly discovered process to explain how lysosomal failure can lead to neurodegenerative disease.

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New evidence affirms depression can be one of the earliest signs of Alzheimer's

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Better treating depression is hypothesized as a potential way to slow the progression of the earliest ...

The link between depression and dementia has been noted by researchers and clinicians for several years now. After all, it seems obvious that one would suffer from feelings of depression as one gets older and experiences the earliest stages of cognitive decline. But a growing body of evidence is building to suggest we may have got the causal direction wrong when considering the associations between depression and dementia.

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Young blood cocktail stops Alzheimer's decline, early clinical trial reports

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The company behind a Phase 2 trial of its proprietary young plasma protein formulation says it ...

Alkahest, a California-based biotech start-up, has just revealed some compelling early results from an ongoing Phase 2 trial into the efficacy of its novel formulation of plasma proteins derived from young blood, developed to slow, or even stop, the cognitive decline associated with Alzheimer’s disease.

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