Tag Archives: Dementia

Clues of link between neurodegeneration and herpes virus infections

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New research presents a novel mechanism that could help explain how viral infections lead to neurodegenerative disease

A new study published in the journal Nature Communications is suggesting a novel causal link between neurodegenerative diseases such as Alzheimer’s and infection with the herpesvirus. The preclinical research indicates a deficiency in a key protein allows the virus to trigger neuronal damage.

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Scientists give lab-grown mini-brains Parkinson’s disease

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Tiny lab-grown mini-brains have now been induced to show pathology features of Parkinson's disease

To help us crack the complex puzzle that is our own brains, scientists have been growing miniature versions in the lab. Now, a team in Singapore has made a major breakthrough by growing mini-brains with the pathological features of Parkinson’s disease for the first time, potentially paving the way towards better treatments.

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Alzheimer’s discovery reveals “Achilles’ heel” of synapse degeneration

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Researchers have uncovered a signaling pathway that could be targeted to prevent the synapse degeneration seen in Alzheimer's disease

Scientists believe one of the key culprits behind the cognitive decline seen in Alzheimer’s are amyloid beta proteins that clump together and disrupt the brain’s synaptic connections, but how they carry out such degeneration has remained unclear. A new study has shone compelling new light on this phenomenon, with the authors demonstrating how these toxic agents take aim at the “Achilles’ heel” of synapses, and better yet, how they might just be stopped.

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New research suggests diabetes drug could slow Alzheimer’s progression

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The research found a link between slower cognitive decline and diabetic patients taking drugs called gliptins

A new study published in the journal Neurology is reporting an association between a particular class of drugs used to treat type 2 diabetes and decreased Alzheimer’s disease biomarkers. It is unclear exactly how these diabetes drugs could exert neuroprotective effects, but Alzheimer’s experts are calling for large-scale clinical trials to explore these potential treatments in non-diabetic groups.

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Can Alzheimer’s be tackled by cutting cholesterol in the brain?

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Scientists have uncovered a mechanism that may allow Alzheimer's to be tackled by controlling cholesterol levels in the brain

One interesting area of Alzheimer’s research focuses on the relationship between cholesterol in the brain and onset of the disease, with studies suggesting the compound can greatly accelerate the buildup of troublesome brain plaques. A new study has expanded our knowledge of this phenomenon by observing it in action in live mice, with the scientists even finding they could intervene in cholesterol production to make the plaques all but disappear.

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AI analyzes gray matter loss to predict the onset of Alzheimer’s

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Scientists have developed a new machine learning algorithm that analyzes gray matter density in the brain as a potential biomarker for Alzheimer's

Advances in artificial intelligence promise to open up all sorts of possibilities when it comes to health care, and analyzing medical images for signs of trouble is already proving to be a great strength of the technology. Scientists at Cambridge University have demonstrated a new type of machine learning algorithm they say can detect structural changes in the brain that are indicative of early dementia, and can be combined with standard memory tests to calculate the likelihood of someone going on to develop Alzheimer’s.

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Gut bacteria from young mice reverse signs of brain aging in old mice

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New research published in the journal Nature Aging is offering some of the first insights into how gut bacteria can potentially influence brain aging in mammals. The study found fecal transplants from young to old mice reversed some aspects of age-rela… Continue reading Gut bacteria from young mice reverse signs of brain aging in old mice→

Preclinical study finds success in reversing age-related memory loss

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An intriguing new study from researchers in the United Kingdom is proposing an innovative method to treat age-related memory loss. The preclinical research shows memory decline in aging mice can be reversed by manipulating the composition of structures… Continue reading Preclinical study finds success in reversing age-related memory loss→

Difficulty hearing speech in noisy rooms may be early sign of dementia

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Experts are divided over whether treating

An impressively large study following more than 80,000 people for 11 years has found that difficulty hearing speech in noisy environments can be an early-warning sign of later-life dementia. The next steps for the research will be to investigate whether immediately treating mid-life hearing impairments can reduce the risk of dementia developing in a person’s senior years.

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