Alzheimer’s Disease – Page 4

Certain personality traits could help protect against dementia

Posted on December 1, 2023 by Paul McClure

Possessing certain personality traits increases the risk of a dementia diagnosis, while others lessen it, research has found

New research has found that some personality traits increase the risk of a dementia diagnosis, whereas others reduce it. Interestingly, no consistent association was seen between personality and dementia-related brain pathology. The findings suggest that targeting personality traits in interventions earlier in life may be a way of reducing dementia risk in the long term.

Category: Health & Wellbeing, Lifestyle

Tags: Dementia, Alzheimer’s Disease, Personality, UC Davis

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Brain cell gene changes linked to neuroinflammation seen in Alzheimer’s

Posted on November 30, 2023 by Paul McClure

A study has linked genetic changes in the brain's immune cells to the neuroinflammation seen in Alzheimer's disease

New research has revealed how genetic changes in a specialized population of brain cells called microglia contribute to neuroinflammation and, in turn, to Alzheimer’s disease. The findings could lead to more effective, targeted therapeutics.

Category: Medical, Science

Tags: Alzheimer’s Disease, Brain, Inflammatory, Genetics, Brigham and Women’s Hospital

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A new cause of brain hemorrhage has been identified

Posted on November 21, 2023 by Bronwyn Thompson

New findings open the door to treatments that ensure the movement of red blood cells through brain capillaries

In a significant development for brain health, scientists have demonstrated for the first time how hemorrhages can occur due to a faulty interaction between aged red blood cells and narrow capillaries. Until now, the cause of this serious condition has been brain bleeding that results from injured or damaged blood vessels.

Category: Medical, Science

Tags: UC Irvine, Brain, Strokes, Blood Pressure, Alzheimer’s Disease, blood vessel

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Alzheimer’s brain effects may be broader than previously thought

Posted on November 17, 2023 by Paul McClure

A study has found that Alzheimer's disease has a broader effect on brain network function than previously thought

Analyzing the functional connectivity of different brain networks, researchers found that, compared to a healthy aging brain, Alzheimer’s disease disrupts areas of the brain beyond those relating to memory and is independent of factors typically associated with the disease, such as amyloid beta levels.

Category: Medical, Science

Tags: Alzheimer’s Disease, Brain, Network, University of Texas, Dementia

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Portable device detects Alzheimer’s and Parkinson’s biomarkers on the spot

Posted on November 15, 2023 by Ben Coxworth

The prototype device, which is currently being commercialized by biotech company Ampera Life

Because of the logistics and invasive procedures involved, many people put off getting tested for Alzheimer’s and Parkinson’s diseases. Thanks to a new portable device, however, such testing could soon be performed non-invasively at just about any location.

Category: Medical, Science

Tags: UC San Diego, Alzheimer’s Disease, Parkinson’s Disease, Neurological, Diagnostic devices

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Drug slows tau’s transformation into toxic tangles seen in Alzheimer’s

Posted on November 9, 2023 by Paul McClure

Researchers have used an experimental drug to slow the phosphorylation of tau, which causes it to aggregate into neuron-damaging tangles in Alzheimer's disease

Researchers have found that when used on monkeys, an experimental drug slowed the process that leads the tau protein to aggregate into neuron-damaging tangles commonly seen in Alzheimer’s disease and improved the animals’ cognitive functioning. The next step is to develop a drug that can be used in humans.

Category: Medical, Science

Tags: Alzheimer’s Disease, Inflammatory, Aging, Yale

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Insulin may be key to the link between obesity and dementia

Posted on November 7, 2023 by Rich Haridy

High-sugar diets may be disrupting the brain's ability to clear out toxic proteins, leading to the development of neurodegenerative diseases

A compelling new study from scientists at the Fred Hutchinson Cancer Research Center is pointing to a possible mechanism linking obesity with neurodegenerative diseases. The detailed work in fruit flies suggests diet-induced insulin resistance can impair the brain’s ability to clear out neuronal debris and contribute to the development of diseases such as Alzheimer’s.

Category: Health & Wellbeing, Lifestyle

Tags: Obesity, Sugar, Insulin, Alzheimer’s Disease, Dementia

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In a first, memory shown to have two distinct past and future paths

Posted on October 24, 2023 by Bronwyn Thompson

For the first time, scientists have teased apart two parts of our memory that makes the all-important whole

For the first time, scientists have found that the region in our brain that houses memory is made up of not one but two sections: one that deals with past experiences of time and places, and one that is more predictive, and actively constructs future behaviors.

Category: Biology, Science

Tags: Cornell University, Cornell, Neuroscience, Memory, Alzheimer’s Disease, Dementia, Brain, Neural Network

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