Alzheimer’s Disease – Page 26

3D brain model offers new evidence linking Alzheimer’s to herpes virus

Posted on May 7, 2020 by Rich Haridy

The 3D brain tissue model shows amyloid beta fibrils (in red), and herpes-infected neurons (in green)

New evidence has been published in the journal Science Advances, adding weight to the link between Alzheimer’s disease and the common herpes virus. The Tufts University study, using a 3D bioengineered brain model, demonstrated how a herpes infection can induce a number of Alzheimer’s features, including neuroinflammation and amyloid plaques.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Brain, Neuroscience, Virus, Tufts University

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Porous nanodevices cage up suspected precursors of Alzheimer’s disease

Posted on May 1, 2020 by Nick Lavars

Researchers have high hopes for new nanodevices (shown here in a Scanning Electron Microscopy (SEM) image) that function like cages to trap peptides associated with Alzheimer's disease

There are many unknowns around the causes of Alzheimer’s, but one of the leading suspects is amyloid beta plaques. These form from amyloid peptides, and while some see these biomarkers as a chance to detect the disease in its early stages, others see them as an opportunity to intervene and possibly stop it altogether. A newly developed nanodevice could give these efforts a potent shot in the arm, by capturing these peptides and clearing them away before they aggregate into harmful plaques.

Category: Medical, Science

Tags: Alzheimer’s Disease, Brain, Argonne National Laboratory

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Discovery links glucose metabolism abnormalities to Alzheimer’s disease

Posted on April 16, 2020 by Rich Haridy

An early biomarker of Alzheimer's may be changes to glucose metabolism protein patterns

A new study, funded by the National Institutes of Health’s National Institute on Aging, is offering novel insights into how protein expressions can be altered during the course of Alzheimer’s disease. The research suggests proteins regulating glucose metabolism and the anti-inflammatory activity of brain immune cells are linked with Alzheimer’s pathology, and could point researchers toward new treatment and diagnostics.

Category: Science

Tags: Alzheimer’s Disease, U.S. National Institutes of Health (NIH), Protein, Inflammatory, Glucose, Brain, Neuroscience, New Atlas Audio

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New study shows how ultrasound technique can treat Alzheimer’s disease

Posted on April 13, 2020 by Rich Haridy

The research investigates how the blood-brain barrier, composed of endothelial cells (imaged above), can be disrupted by focused ultrasound and potentially help treat Alzheimer's disease

A new study led by Australian researchers is offering further insight into how a novel ultrasound technique could help treat Alzheimer’s disease. The findings describe how focused ultrasound can weaken the blood-brain barrier in brain cells from Alzheimer’s patients, potentially improving the uptake of drugs designed to treat the disease.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Ultrasound, QIMR Berghofer, Neuroscience

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Alzheimer’s trial supports high amyloid levels as early sign of disease

Posted on April 7, 2020 by Rich Haridy

An ongoing long-term trial suggests high levels of amyloid proteins in the brain do serve as an early sign of Alzheimer's disease before cognitive decline becomes apparent

A new study presenting the first data from a long-running US government trial is suggesting high levels of amyloid proteins in the brains of cognitively normal older adults can be an effective presymptomatic sign of early stage Alzheimer’s disease.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Neuroscience, Brain, U.S. National Institutes of Health (NIH), Protein, New Atlas Audio

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Blood-based biomarker discovery points to early-stage Alzheimer’s test

Posted on April 3, 2020 by Rich Haridy

A UC San Diego study has found evidence that high levels of a specific type of exRNA in blood samples predicts the onset of Alzheimer's two years before symptoms appear

New research from the University of California San Diego is suggesting high levels of a certain blood-based biomarker may serve as an early warning sign of Alzheimer’s disease, two years before symptoms develop. The preliminary study has yet to be verified in larger cohorts of patients.

Category: Health & Wellbeing, Lifestyle

Tags: Alzheimer’s Disease, Neuroscience, Brain, Blood, RNA, Diagnose, UC San Diego, New Atlas Audio

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Large study finds asprin does not reduce risk of developing Alzheimer’s

Posted on March 27, 2020 by Nick Lavars

A new study has found that daily consumption of aspirin offers no benefit when it comes to cognitive impairment associated with dementia and Alzheimer's

The idea that regular consumption of aspirin can reduce the symptoms of dementia has been the source of much contention in scientific circles. Researchers behind a new large-scale study involving almost 20,000 patients are the latest to weigh in on this debate, with their multi-year investigation uncovering no evidence of therapeutic benefit when it comes to staving off this Alzheimer’s and other types of cognitive impairment.

Category: Medical, Science

Tags: Monash University, Alzheimer’s Disease, Dementia, New Atlas Audio

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How the brain’s immune cells both help and harm in cases of Alzheimer’s

Posted on March 19, 2020 by Rich Haridy

Microglia, the brain's immune cells, are being investigated for the role they may play in the progression of Alzheimer's disease

A trio of new studies are investigating the role our brain’s immune cells play in the progression of Alzheimer’s disease. Researchers are revealing how these immune cells can contribute to neurodegeneration, and how they may be harnessed to prevent neuron damage.

Category: Science

Tags: Alzheimer’s Disease, Dementia, The Immune System, Inflammatory, Neuroscience

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Cambridge study adds evidence linking brain inflammation with dementia

Posted on March 17, 2020 by Rich Haridy

A new study has found a link between the build-up of damaging toxic proteins and the presence of neuroinflammation in three different types of dementia

A new imaging study has found neuroinflammation may be more common in neurodegenerative diseases than previously suspected. The Cambridge research revealed brain inflammation to be a common thread across three different types of dementia.

Category: Medical, Science

Tags: Dementia, Alzheimer’s Disease, Inflammatory, The Immune System, Neuroscience, Brain, Medical Imaging, University of Cambridge

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Newly discovered mechanism links sleep regulation and Alzheimer’s

Posted on March 16, 2020 by Rich Haridy

A new study is the first link to sleep and neurodegeneration to the same signaling pathway in the brain

The link between diseases such as Alzheimer’s and sleep loss has been frequently cited by researchers, and a new study led by scientists from the University of Pennsylvania has discovered a signaling pathway that both regulates sleep and controls the protein aggregations commonly associated with neurodegeneration. It’s hoped the discovery will lead to better therapies to reduce the risk of Alzheimer’s and improve sleep quality.

Category: Health & Wellbeing, Lifestyle

Tags: Sleeping, Sleep, Alzheimer’s Disease, Dementia, Protein, Neuroscience, University of Pennsylvania

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