New evidence affirms apathy is an early sign of dementia

New research builds on prior work suggesting apathy is an early sign of dementia

A growing body of research is beginning to suggest severe apathy in older adults is an early sign of dementia. New research from the University of California, San Francisco, with support from the National Institute on Aging, is now offering one of the first longitudinal studies to show apathy could be an early visible symptom of cognitive decline.

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New evidence links age-related cognitive decline & the gut microbiome

A mouse study has revealed young mice display learning and memory impairments following a fecal transplant from older animals

Scientists from the UK and Italy have found fecal transplants from old mice to young mice result in the younger animals displaying learning and memory impairments. The findings build on a growing body of research linking age-related cognitive decline with gut microbiome changes.

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Link between Alzheimer’s and sleep apnea affirmed in brain tissue study

Brain tissue analysis revealed sleep apnea generates similar patterns of toxic protein accumulation to what researchers see in Alzheimer's disease

A new study, from a team of Australian and Icelandic scientists, is offering some of the strongest evidence to date linking Alzheimer’s disease and sleep apnea. The research, based on studying autopsied brain tissue, shows how the toxic protein aggregations commonly associated with Alzheimer’s seem to start and spread in the same way in the brains of patients with sleep apnea.

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Common diabetes drug linked to lower dementia rates

New research found the rate of cognitive decline was similar between non-diabetics and diabetics taking a medication called metformin

New Australian research has found older diabetic patients using a drug called metformin experience slower rates of cognitive decline and dementia compared to those not using the medication. The findings build on the growing body of evidence suggesting this common drug generates compelling anti-aging effects.

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Promising Alzheimer’s biomarker detected in eyes for the first time

A protein associated with neurodegeneration, previously detected in blood samples, has now been found in eye fluid

A protein, previously found to be an effective blood-based biomarker of neurodegenerative diseases such as Alzheimer’s, has for the first time been detected in the eye. The discovery lays the foundation for promising new diagnostic eye tests hoping to catch neurodegenerative diseases years before symptoms appear.

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Synthetic molecules repair mouse brain function lost to disease and injury

Newly created synthetic molecules could help repair brain connections lost to disease or injury

The brain is an incredibly complex network of connections, but in some neurological disorders those connections can be lost. Researchers from the UK, Germany and Japan have now created synthetic molecules that may be able to help patch them up, with tests in cultured cells and mice showing promise in treating disease and injury.

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Poor sleep may predict Alzheimer’s onset years before symptoms appear

Research suggests fragmented sleep and low-levels of slow-wave sleep can predict the rate by which toxic Alzheimer's-causing proteins accumulate in one's brain

A robust new study from researchers at UC Berkeley has found a consistent association between poor sleep and greater accumulation of the toxic proteins thought to be the pathological cause of Alzheimer’s disease. The researchers suggest fragmented sleep could be an effective early way to predict those most at risk of developing the neurodegenerative disease.

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Continue reading Poor sleep may predict Alzheimer’s onset years before symptoms appear

Poor sleep may predict Alzheimer’s onset years before symptoms appear

Research suggests fragmented sleep and low-levels of slow-wave sleep can predict the rate by which toxic Alzheimer's-causing proteins accumulate in one's brain

A robust new study from researchers at UC Berkeley has found a consistent association between poor sleep and greater accumulation of the toxic proteins thought to be the pathological cause of Alzheimer’s disease. The researchers suggest fragmented sleep could be an effective early way to predict those most at risk of developing the neurodegenerative disease.

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Continue reading Poor sleep may predict Alzheimer’s onset years before symptoms appear

New evidence of link between inflammation and Alzheimer’s disease

Researchers claim to have identified the first direct mechanism linking inflammation with the neurodegeneration seen in Alzheimer's disease

Researchers from the Sloan Kettering Institute have uncovered what they say is the first direct evidence to show how a dysfunctional immune response can contribute to the pathology of Alzheimer’s disease. The study, published in the journal Nature, adds to a growing body of evidence highlighting the role of neuroinflammation in dementia and cognitive decline.

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AI algorithm detects signs of Alzheimer’s disease through language

AI algorithms that analyze the language used by Alzheimer's sufferers could become a useful tool in diagnosing the disease in its early stages

With no cure and no straightforward way of diagnosing the disease, scientists are exploring every avenue when it comes to detecting Alzheimer’s during its early stages. One group of researchers has turned its attention to subtle differences in the language of sufferers, and have developed an AI tool they say can pick up on these as a way of potentially screening for the disease.

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