Alzheimer’s drug trial raises concerns for accelerating cognitive decline

A drug that reduces iron levels in the brain also has a profound effect on Alzheimer's disease progression

While growing evidence suggests that there’s a link between blood iron levels and the development of Alzheimer’s disease, new research investigating the effects of an available iron-reducing drug has raised concerns about its use as a treatment for the condition.

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Category: Alzheimer’s & Dementia, Brain Health, Body & Mind

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‘Brain stars’ store our memories like a microscopic filing cabinet

Memory storage and retrieval may be able to be targeted thanks to new discovery

Fascinating new findings into how clusters of ‘brain stars’ retain memories has changed what we know about how they’re held in our minds.

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Alzheimer’s domino effect hypothesis opens up new treatment targets

Researchers have created a 'pathology clock' of how brain cells are damaged by Alzheimer's disease over time

By obtaining high-resolution images of Alzheimer’s disease-affected brain cells as the condition progresses, researchers have identified the specific neurons that are damaged. The information the ‘cell atlas’ provides highlights potential new treatment targets.

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Alzheimer’s-linked tau protein gets a surprising redemption story

The tau protein is not such a 'bad guy' after all

A new study has somewhat redeemed the tau protein, which up to now has been associated with the development of Alzheimer’s disease. Turns out, the protein has a ‘good guy’ role, helping to protect against harmful free radicals in the brain and promoting healthy aging.

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“Suspended animation” drug could buy time in medical emergencies

A drug already used to treat Alzheimer's could find a second use in inducing a hibernation-like state, to save lives during medical emergencies

In a medical emergency, quick treatment is critical. But a widely used drug could be repurposed to induce a hibernation-like state, to slow down organ damage and save lives by giving patients more time to reach a hospital.

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Common drug restores youthful function to clean up aging brains

Restoring the brain's ability to drain itself of dirty fluid could go a long way toward fighting diseases like Alzheimer's and Parkinson's

A drug used to induce labor in pregnant women has been shown to reactivate tiny waste-clearing pumps in the brains of old mice. The finding could hold promise as a new way to fight Alzheimer’s and Parkinson’s diseases and overall cognitive decline.

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Common drug restores youthful function to clean up aging brains

Restoring the brain's ability to drain itself of dirty fluid could go a long way toward fighting diseases like Alzheimer's and Parkinson's

A drug used to induce labor in pregnant women has been shown to reactivate tiny waste-clearing pumps in the brains of old mice. The finding could hold promise as a new way to fight Alzheimer’s and Parkinson’s diseases and overall cognitive decline.

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Continue reading Common drug restores youthful function to clean up aging brains

New compound flips memory back on in Alzheimer’s cases

A new molecule that switched memory and cognition back on in mice with Alzheimer's could one day do the same for humans, as illustrated in this generative image

Instead of focusing on fighting the plaques linked to Alzheimer’s, researchers took a look at boosting electrical oscillations in the brain. The molecule they invented got the job done in mice, offering hope for a new treatment path for humans.

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14 things you can do to prevent or delay the onset of dementia

Addressing 14 risk factors could prevent or delay the onset of dementia

A new report by world-leading experts lists 14 modifiable risk factors associated with 40% of all dementia cases that, if addressed by people across their lifespan, could reduce the likelihood of developing the condition or delay its onset.

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“Cat poop” brain parasite could be hijacked to deliver drugs

The common

Brain parasites are something that most people would naturally want to avoid, but maybe they can be used for good. A new study has found that a common brain parasite could be engineered to deliver drugs past the blood-brain barrier.

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