New drug triggers “calcium storm” to choke cancer cells to death

No matter how important something is, too much of anything is bad for you. Scientists have now put that principle to work to kill cancer, with a new drug that causes calcium to build up and choke the tumor to death.Continue ReadingCategory: Medical, Sc… Continue reading New drug triggers “calcium storm” to choke cancer cells to death

Novel ‘Chimera’ drug targets the ‘undruggable’ Parkinson’s protein

Researchers have developed a novel two-headed drug to treat Parkinson's disease

Inspired by a creature from Greek mythology, researchers have created a ‘two-headed’ drug that prevents the production of the toxic protein linked to Parkinson’s disease before destroying the RNA machinery that makes it. The novel drug may be a way of slowing or even stopping the disease’s progression.

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New antibiotic family kills superbugs in a way they can’t resist

Antibiotic-resistant bacteria are poised to become a global health concern in the coming decades. In the race to develop new weapons, scientists from Texas A&M have created a novel family of antibacterial polymers that can kill ‘superbugs’ in a way the… Continue reading New antibiotic family kills superbugs in a way they can’t resist

Single-dose drug to quash anxiety passes another trial milestone

An effective single-dose, long-term treatment for anxiety could be within reach, with the phase 2b clinical trial of MM-120 reported to have passed the stage with flying colors. The makers, MindMed, now plan to hold an end-of-phase meeting with the US … Continue reading Single-dose drug to quash anxiety passes another trial milestone

World-first: Daily tablet slows diabetes progression in clinical trial

A world-first clinical trial has found that baricitinib, a drug commonly prescribed for rheumatoid arthritis, preserved the pancreatic cells’ ability to produce their own insulin and slowed the progression of type 1 diabetes in those recently diagnosed… Continue reading World-first: Daily tablet slows diabetes progression in clinical trial

Slow-release diabetes drugs could cut shots from daily to 3 times a year

Managing diabetes usually involves regular shots of insulin or other drugs, but soon patients might only need to inject themselves a few times a year. Stanford has developed a hydrogel-based delivery system that slowly releases drugs over months to con… Continue reading Slow-release diabetes drugs could cut shots from daily to 3 times a year

Non-benzodiazepine anti-anxiety drug performs well due to innovative tech

A proof-of-concept clinical trial of a non-benzodiazepine drug, a version of a naturally occurring neuroactive steroid, has shown that it’s as effective as alprazolam, better known as Xanax, at reducing anxiety. Critical to the trial’s success was tech… Continue reading Non-benzodiazepine anti-anxiety drug performs well due to innovative tech

New drug given every few months reduces high blood pressure in trial

People with high blood pressure may soon be able to swap the daily pills for an injection every few months. A phase 2 clinical trial has shown that a drug called Zilebesiran can drastically reduce blood pressure for long periods of time with no side ef… Continue reading New drug given every few months reduces high blood pressure in trial

Diabetes-delaying drug shows promise in phase 3 clinical trial

A phase 3 clinical trial has shown that a drug called teplizumab can slow down progression of type 1 diabetes in children and teenagers with a recent diagnosis. The trial’s success could help expand the options for patients and relieve some burdens of … Continue reading Diabetes-delaying drug shows promise in phase 3 clinical trial

Lifestyle intervention plus Mounjaro leads to additional weight loss

The latest findings from phase 3 clinical trials of tirzepatide, sold as Mounjaro, have demonstrated that if taken after an initial weight loss brought about by diet and lifestyle changes, the drug can lead to significant additional weight reduction.Co… Continue reading Lifestyle intervention plus Mounjaro leads to additional weight loss