Discovery of mechanical itch protein hints at new treatments for eczema

Scientists investigating the cellular basis for itching have made an important discovery, and one that could lead to new treatments of chronic conditions like eczema. The breakthrough centers on what’s known as mechanical itching, with the research tea… Continue reading Discovery of mechanical itch protein hints at new treatments for eczema

Protein linked to alcoholism relapse offers novel target for treatment

Alcohol use disorder is a leading cause of preventable death and a complex disease, but by understanding its effects on brain function scientists hope to lower the risk and rates of relapse. The latest finding in this space comes from Scripps Research … Continue reading Protein linked to alcoholism relapse offers novel target for treatment

Smartphone app calculates your genetic risk for heart disease

A new smartphone app called MyGeneRank has been developed by scientists at the Scripps Research Translational Institute. The app calculates a person’s genetic risk for coronary artery disease and directs those found to be at high risk to appropriate me… Continue reading Smartphone app calculates your genetic risk for heart disease

Blocking metabolic effects of obesity potentially prevents diabetes

Scientists at the Scripps Research Institute have spent the past few years studying a promising but problematic signaling pathway they believe can be targeted to prevent type 2 diabetes. The team has now demonstrated how this pathway can be temporarily… Continue reading Blocking metabolic effects of obesity potentially prevents diabetes

Can Alzheimer’s be tackled by cutting cholesterol in the brain?

Scientists have uncovered a mechanism that may allow Alzheimer's to be tackled by controlling cholesterol levels in the brain

One interesting area of Alzheimer’s research focuses on the relationship between cholesterol in the brain and onset of the disease, with studies suggesting the compound can greatly accelerate the buildup of troublesome brain plaques. A new study has expanded our knowledge of this phenomenon by observing it in action in live mice, with the scientists even finding they could intervene in cholesterol production to make the plaques all but disappear.

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“Undruggable” cancer protein targeted by compound from shrub root

Scientists at Purdue University and the Scripps Research Institute have identified a natural compound from a common shrub that could help fight cancer. The compound is the first found to inhibit a cancer protein that was previously considered “undrugga… Continue reading “Undruggable” cancer protein targeted by compound from shrub root

New molecules rebalance gut bacteria to cut cholesterol in mice

Recent research is continuing to illuminate the role gut bacteria can play in all sorts of health outcomes, uncovering its ties with depression, obesity and various autoimmune diseases, just to offer a few examples. A new study has delved into their im… Continue reading New molecules rebalance gut bacteria to cut cholesterol in mice

Deep sea expedition uncovers 30 new species, plus longest-known animal

Forget space – the oceans are Earth’s final frontier. Even after centuries of exploration we’re still only just scratching the surface of what lives down there. The latest case in point is a diving expedition off the coast of Western Australia, which h… Continue reading Deep sea expedition uncovers 30 new species, plus longest-known animal

Life's building blocks spontaneously self-assemble in primordial soup experiment

Researchers have shown that amino acids, the building blocks of life, stack themselves readily under the ...

Exactly how life sprung out of non-living matter is one of biology’s biggest mysteries. But with continued research into our own origin story, it’s starting to seem like life on early Earth was just itching to be born. In new research from Georgia Tech and the Scripps Research Institute, scientists cooked up a “primordial soup” and found that some of the crucial building blocks of life spontaneously stacked themselves in a surprisingly efficient way.

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