Molecular “off” switch keeps cancer immunotherapy from turning deadly

One of the most promising cancer treatments is CAR T cell immunotherapy, where the body’s natural tumor-hunting cells are supercharged – but it can backfire with potentially deadly results. Now, scientists have engineered these immune cells to have off… Continue reading Molecular “off” switch keeps cancer immunotherapy from turning deadly

Artificial enzyme could slow Parkinson’s by targeting protein clumps

Johns Hopkins scientists have created artificial enzymes that may slow the progression of Parkinson's disease by halting the spread of pathogenic protein clumps

Neurodegenerative diseases like Parkinson’s are characterized by clumps of misfolded proteins accumulating and killing brain cells. Now, researchers at Johns Hopkins have developed an artificial enzyme that may stop these clumps from spreading, providing a new potential treatment for Parkinson’s.

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DeepMind AI solves 50-year protein folding problem in “stunning advance”

While some of the applications for artificial intelligence involve say, winning games of Texas hold’em or recreating pretty paintings, there are areas where the technology could have truly profound consequences. Among those is medical care, and a major… Continue reading DeepMind AI solves 50-year protein folding problem in “stunning advance”

Decoy molecule draws deadly mosquito-borne virus away from the brain

Venezuelan equine encephalitis virus (VEEV) is a mosquito-borne virus that, in the worst case scenario, can infect the brain and become deadly. It’s notoriously difficult to treat, but now scientists have discovered the protein it latches onto – and us… Continue reading Decoy molecule draws deadly mosquito-borne virus away from the brain

Illuminating the Inner Workings of a Venus Flytrap

As a carnivorous plant, Venus flytraps have always been a fascinating subject of study. One of their many mysteries is how they differentiate an insect visit from less nutritious stimulants such as a windblown pebble. Now scientists are one step closer to deciphering the underlying mechanism, assisted by a new …read more

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Gene therapy restores partial vision to totally blind mice

In some forms of blindness, certain parts of the eye still work but damage to light-sensitive cells disrupts vision. Now, researchers at a company called Nanoscope have used gene therapy to bypass damaged cells and restore some level of vision to mice … Continue reading Gene therapy restores partial vision to totally blind mice

Protein injections into testes could treat male infertility

Male infertility is a serious issue, often caused by low sperm counts. Now, researchers at Seoul National University have developed a way to deliver nanoparticles loaded with certain proteins directly into the testes. In tests in mice, previously infer… Continue reading Protein injections into testes could treat male infertility

Wasp venom peptides show potential as potent antibiotic candidate

With antibiotic-resistant bacteria poised to become a huge health problem in the coming decades, the world desperately needs new drugs and treatments. Now, researchers at the University of Pennsylvania have engineered new antimicrobial molecules from w… Continue reading Wasp venom peptides show potential as potent antibiotic candidate

Promising “molecular tweezer” Parkinson’s therapy looks to human trials

A novel therapy using molecular tweezers has proven safe and effective in animal models and researchers are now looking ahead to human trials

New research published in the journal Nature Communications reveals a novel drug, designed to break up the aggregations of toxic proteins associated with Parkinson’s disease, can effectively slow the disease in mouse models. The researchers are now looking at moving toward human trials.

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New drug candidate “shreds” cancer-causing protein in early lab tests

Researchers in Germany have developed a new drug that can act like a “shredder” for proteins implicated in causing cancer. In tests on lab-grown cancer cells, the drug worked to kill the tumors, suggesting a new pathway to a treatment for the disease.C… Continue reading New drug candidate “shreds” cancer-causing protein in early lab tests