Collaborate Disseminate
Robust new research, published in the journal Science, has revealed a microbial mechanism connecting obesity with heart disease. The study describes how a high-fat diet damages intestinal cells, leading to an imbalance of bad bacteria that produce meta… Continue reading How gut bacteria pave the road from high-fat diet to heart disease
While jogging, cycling, swimming and other forms of cardio exercise are well-known ways to burn calories, the relationship between weight training and weight loss is more complex. A new study has dug into the molecular underpinnings of this and identif… Continue reading How weight training instructs cells to enter fat-burning mode
There are different types of fat in the body that perform very different roles, and by promoting the production of one over the other scientists hope to develop new forms of treatment for conditions like obesity and diabetes. Scientists in China have i… Continue reading Immune signaling molecule boosts fat-burning to prevent obesity
Scientists in the US investigating the biological mechanisms behind fat burning have identified a protein that plays a key role in regulating metabolism, and demonstrated how blocking its activity can boost the process in mice. The protein in question,… Continue reading Protein that “hacks” energy pipeline offers target for fat-burning drugs
Scientists looking for novel ways to treat type 2 diabetes have stumbled across a mechanism by which the immune system can trigger the secretion of fat cells through the skin. The mechanism may translate from animal studies into humans, but turning it … Continue reading Mice sweating fat raises prospect of unusual anti-obesity therapy
A clinical trial testing fecal transplants in severely obese subjects with metabolic syndrome has found the treatment to be only beneficial when accompanied by non-fermentable fiber supplements. The phase 2 trial saw improvements in insulin sensitivity… Continue reading Fecal transplant plus fiber successfully treats metabolic syndrome
UK and University of Otago researchers have presented a “world-first weight loss device,” which attaches to the teeth and prevents patients from opening their mouths wider than 2 mm using “magnetic devices and custom-manufactured locking bolts.”Continu… Continue reading DentalSlim weight-loss device literally locks your mouth shut
By better understanding the biological underpinnings of different types of fat in the body, scientists hope to uncover new ways to tackle obesity and conditions relating to it. Researchers have now found that increasing levels of a certain protein in b… Continue reading Protein found to boost fat-burning, lower risk of diabetes
The US Food and Drug Administration (FDA) has approved a new weight management drug called Wegovy (semaglutide). The drug was first approved as a type 2 diabetes treatment in 2017 and has subsequently been described as a “game-changer” for obese or ove… Continue reading FDA approves “game-changing” new weight loss drug
The brain functions behind the feelings of fullness that stop us from reaching for another bite are highly complex, but by better understanding the intricacies of these systems scientists hope to uncover new treatments for conditions like obesity. Rese… Continue reading Brain circuit behind satiation offers new target for obesity treatment