Trial finds insulin nasal spray may slow age-related cognitive decline

The results of a small Phase 2 clinical trial offers promising signs that daily doses of an insulin nasal spray could be used to slow age-related cognitive decline. The trial found the treatment to be effective in elderly subjects both with and without… Continue reading Trial finds insulin nasal spray may slow age-related cognitive decline

Promising new drug target to treat diabetes and other metabolic diseases

A new preclinical study has demonstrated how an experimental drug can treat type 2 diabetes by increasing the expression of a recently discovered protein found to influence insulin signaling in cells. Across several mouse studies, the research shows th… Continue reading Promising new drug target to treat diabetes and other metabolic diseases

Blocking cellular pathway delays or prevents onset of diabetes in mice

Researchers have identified a cellular pathway that seems to play a role in the onset of type 1 diabetes, and found that blocking it could help prevent the disease

Type 1 diabetes begins when beta cells in the pancreas die off, meaning a patient can no longer produce enough insulin. Scientists have now identified a cellular pathway that can contribute to the death of these cells, and found that blocking it in mice and human cells keeps the beta cells alive for longer, delaying or preventing the onset of diabetes.

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Continue reading Blocking cellular pathway delays or prevents onset of diabetes in mice

Blocking cellular pathway delays or prevents onset of diabetes in mice

Researchers have identified a cellular pathway that seems to play a role in the onset of type 1 diabetes, and found that blocking it could help prevent the disease

Type 1 diabetes begins when beta cells in the pancreas die off, meaning a patient can no longer produce enough insulin. Scientists have now identified a cellular pathway that can contribute to the death of these cells, and found that blocking it in mice and human cells keeps the beta cells alive for longer, delaying or preventing the onset of diabetes.

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Category: Medical, Science

Tags: , , , ,

Continue reading Blocking cellular pathway delays or prevents onset of diabetes in mice

New study suggests that insulin could be delivered via cheek patches

Diabetics typically have to receive insulin via daily injections, or sometimes even from implanted pumps. According to a new study, however, a simple inner-cheek patch could one day provide a far less painful and invasive alternative.Continue ReadingCa… Continue reading New study suggests that insulin could be delivered via cheek patches

Insulin-alternative hormone could open new type of diabetes treatment

Insulin is known for regulating blood glucose levels, and issues with its production lead to diabetes. But now, scientists at the Salk Institute have identified another molecular pathway that regulates blood glucose, which could open up a brand new ave… Continue reading Insulin-alternative hormone could open new type of diabetes treatment

Harvard team disables newly discovered hormone to reverse diabetes in mice

Scientists at Harvard University have made a breakthrough that implicates a newly discovered hormone in the onset of diabetes, and shown how it can be targeted to reverse the effects of the disease. The results of the experiments in mice suggest the sa… Continue reading Harvard team disables newly discovered hormone to reverse diabetes in mice

“Functional cure” for type 1 diabetes passes first human trials

A pair of new studies are reporting results from a landmark type 1 diabetes human clinical trial testing the safety and efficacy of an implantable device containing stem cells designed to mature into insulin-secreting cells. The experimental implant wa… Continue reading “Functional cure” for type 1 diabetes passes first human trials

Oral insulin pill treats, and even prevents, type 1 diabetes in mice

Researchers at Yale have developed a new oral medication for type 1 diabetes. In tests in mice, not only did the drug quickly adjust insulin levels, it also restored metabolic functions and reversed inflammation, opening up a potential way to prevent t… Continue reading Oral insulin pill treats, and even prevents, type 1 diabetes in mice

Experimental drugs clear zombie-like cells and apply brakes to diabetes

Zombie-like cells that have stopped dividing in the human body and accumulate as we age, known as senescent cells, continue to find themselves at the center of all kinds of medical breakthroughs. A new study has explored how these damaged, lingering ce… Continue reading Experimental drugs clear zombie-like cells and apply brakes to diabetes