German man third to be completely cured of HIV after stem cell transplant

A 53-year-old from Düsseldorf in Germany has become the third person in the world to be completely cured of HIV following a stem cell transplant using donor cells with a particular genetic mutation.Continue ReadingCategory: Medical, ScienceTags: HIV an… Continue reading German man third to be completely cured of HIV after stem cell transplant

Major setback as another large ongoing Phase 3 HIV vaccine trial fails

In a blow to researchers all across the world, the only HIV vaccine currently in Phase 3 human trials has been deemed a failure and studies have been discontinued. The experimental vaccine was being tested in thousands of participants across Europe, No… Continue reading Major setback as another large ongoing Phase 3 HIV vaccine trial fails

Stem cell HIV cure proves successful in oldest patient to date

A 66-year-old man has become the fourth patient to be effectively cured of a HIV infection after undergoing a stem cell transplant from a donor with a rare genetic mutation that has been linked to HIV resistance. The man, now in remission for 17 months… Continue reading Stem cell HIV cure proves successful in oldest patient to date

Moderna kicks off Phase 1 trial of 3 different mRNA HIV vaccines

Biotechnology company Moderna, in association with The National Institute of Allergy and Infectious Diseases, has kicked off a Phase 1 human trial testing three different mRNA vaccine formulations designed to induce immunity against HIV. The trial is t… Continue reading Moderna kicks off Phase 1 trial of 3 different mRNA HIV vaccines

Newly discovered HIV variant exposes myth of “mild” viral evolution

Research led by the University of Oxford’s Big Data Institute has discovered a novel, highly virulent strain of HIV in the Netherlands. The new HIV variant results in a higher viral load and faster disease progression. The evolution of the variant, whi… Continue reading Newly discovered HIV variant exposes myth of “mild” viral evolution

Refined “kick and kill” strategy eliminates HIV in infected mice

HIV is tricky to eliminate thanks to its tendency to hide out in cellular reservoirs, but a growing body of work shows that a cure might be possible. In a new study, improvements to a previous “kick and kill” technique were able to completely clear out… Continue reading Refined “kick and kill” strategy eliminates HIV in infected mice

Innovative mRNA study closes in on elusive HIV vaccine

New research led by scientists from the National Institute of Allergy and Infectious Diseases is showing promising preclinical signs for an experimental mRNA vaccine targeting HIV. The sophisticated vaccine was found to generate robust responses in mic… Continue reading Innovative mRNA study closes in on elusive HIV vaccine

Drugs that trip cellular alarm could help clear out hibernating HIV

HIV can currently be managed with a lifelong daily drug regimen, but unfortunately the infection can’t be eliminated entirely. Now, researchers have found a potential way to trip a cellular “alarm” to alert the immune system to clear out infected cells… Continue reading Drugs that trip cellular alarm could help clear out hibernating HIV

Cancer immunotherapy hunts down hidden HIV in mouse study

HIV is an insidious virus, able to hibernate inside infected cells ready to re-emerge if treatment is stopped. Now, a team of researchers has found a way to shrink that viral reservoir by adapting a cancer immunotherapy technique to supercharge immune … Continue reading Cancer immunotherapy hunts down hidden HIV in mouse study