Unique real-world data shows early retirement hastens cognitive decline

New research from economists at Binghamton University shows early retirement can be linked to an acceleration of age-related cognitive decline. Looking at data from a unique pension program in China, the findings suggest increased social activity may m… Continue reading Unique real-world data shows early retirement hastens cognitive decline

Another controversial FDA approval for a new Alzheimer’s medication

The approval of a drug for Alzheimer's follows several recently reported deaths of clinical trial participants

The U.S. Food and Drug Administration (FDA) has approved a new drug for patients in the early-stages of Alzheimer’s disease. Called Leqembi (lecanemab) the treatment was heralded last year as a major breakthrough in Alzheimer’s therapy following early Phase 3 data indicating it could slow the progression of cognitive decline. But growing concerns over the drug’s safety and real-world efficacy have led to acrimonious division amongst researchers, with some suggesting the drug should not be authorized for wide use.

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Signs of Alzheimer’s found in brains of beached dolphins

New research bolsters a hypothesis dubbed

Could the phenomenon of whale and dolphin strandings be due to Alzheimer’s-like cognitive deficits in pod leaders that draw groups into shallow waters? A new study looking at brain tissue from stranded dolphins reveals pathological signs that resemble what is seen in human patients with Alzheimer’s disease.

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New evidence links nasal viral infections to rapid Alzheimer’s progression

A new study has found evidence that viral infections in the olfactory system could trigger a cascade of events that can lead to Alzheimer's disease

A new study has presented more evidence backing up a hypothesis suggesting viral infections in the olfactory system can accelerate the progression of Alzheimer’s disease (AD). Instead of focusing on specific viruses, the research looked at the relationship between biomarkers of viral infections and neurodegeneration in the hippocampus.

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First human trials test light & sound therapy for Alzheimer’s disease

A promising new therapy for Alzheimer's involves exposure to a 40-Hz flickering light and sound tone for an hour a day

A new study published in the journal PLoS ONE has reported on the first human tests of an experimental therapy using sound and light to treat Alzheimer’s disease (AD). The initial findings are promising, with the unique treatment leading to some neurological and cognitive improvements, but the small trial size means more study is needed before anyone can say this type of therapy works.

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Risk of Alzheimer’s linked with genetic propensity for ADHD

A new study has found people with a high genetic risk score for ADHD display faster rates of cognitive decline compared to a matched group without the same genetic propensity

A genetic predisposition to attention-deficit/hyperactivity disorder (ADHD) has been linked to an increased risk of cognitive decline and Alzheimer’s disease in old age, according to new research from the University of Pittsburgh. The findings are the first to associate ADHD genetic risk with age-related cognitive impairment.

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Hearing aids slow cognitive decline, but reasons why still a mystery

A new meta-study has found using a hearing aid can be linked to lower risk of cognitive decline but it's still unclear exactly how the devices are preventing dementia

A first-of-its-kind meta-analysis comprising more than 100,000 participants has found a significant association between the use of hearing aids and a reduced risk of dementia. The findings raise the curious suggestion that using hearing restoration devices could somehow slow the progression of cognitive decline.

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Harvard study links severe COVID with genetic signs of brain aging

The study found severe COVID was linked with many of the same gene expression changes in brain tissue seen in old age

A study looking at post-mortem brain tissue samples has found severe COVID-19 is associated with molecular signs of brain aging. The study identified gene expression changes in the brains of deceased COVID patients that resemble what is seen in old age, and the researchers warn potential long-term neurological problems could emerge in the years following the pandemic.

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Yale study uncovers new potential root cause of Alzheimer’s disease

A microscope image of amyloid plaques (blue) surrounded by swelling in axons (purple)

Scientists at Yale University have uncovered an overlooked mechanism that may be behind the symptoms of Alzheimer’s disease. The team points the finger at small swellings on axons near plaques that build up in the brain, and identified a protein that could be a biomarker for early detection of the disease as well as a target for future treatments.

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Simple urine test proposed as early diagnostic tool for Alzheimer’s

New research raises the possibility of a test that could detect Alzheimer's in its early stages

Alzheimer’s is a slow-moving neurodegenerative disease. Decades can pass before clinical symptoms appear, and even when they do it’s challenging to identify the disease in patients with mild cognitive impairment.

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