Groundbreaking use of CRISPR selects sex of mice with 100% efficiency

Researchers at Francis Crick Institute and the University of Kent have used the CRISPR gene-editing system to produce litters of mice that are 100 percent either male or female. The technique could help prevent the unnecessary culling of animals of unw… Continue reading Groundbreaking use of CRISPR selects sex of mice with 100% efficiency

Gut microbiome genetically edited in live mice for the first time

Scientists at the University of California San Francisco (UCSF) have successfully edited the genome of bacteria in the gut microbiome of living mice, for the first time. Bacteria-hunting viruses are loaded with the CRISPR gene-editing system, in a brea… Continue reading Gut microbiome genetically edited in live mice for the first time

Gene-edited barley to bolster beer production in face of climate change

Climate change is expected to have a big impact on crop yields and food security over the coming decades, as farmers contend with rising temperatures and increasingly abnormal conditions. Scientists working on solutions to this problem continue to demo… Continue reading Gene-edited barley to bolster beer production in face of climate change

CRISPR stem cell therapy grants lizards new regeneration powers

Lizards are famous for their regeneration, able to regrow their tails on demand, but the new tail is not quite perfect. Now, researchers at the University of Southern California (USC) have used stem cell therapy to let lizards grow better tails – bones… Continue reading CRISPR stem cell therapy grants lizards new regeneration powers

Beyond CRISPR: New class of gene-editing enzymes discovered

One of the most revolutionary discoveries of the century, the CRISPR gene-editing system is built on a bacterial defense mechanism that allows scientists to make precise edits to DNA. Now scientists at MIT have discovered a new class of enzymes called … Continue reading Beyond CRISPR: New class of gene-editing enzymes discovered

Genetics startup turns to CRISPR to resurrect the woolly mammoth

A new genetics company called Colossal has grand plans to revive the woolly mammoth and reintroduce the species to the Arctic tundra. And it isn’t meant to be just a tourist-trap Jurassic Park either – the aim is to restore a long-lost ecosystem which … Continue reading Genetics startup turns to CRISPR to resurrect the woolly mammoth

“Mini” CRISPR tool reworks inactive protein for better gene editing

The CRISPR gene-editing system is usually associated with the Cas9 protein, but that’s not the only option out there. Scientists at Stanford have now developed a CRISPR tool called CasMINI, using a much smaller protein that should be able to enter huma… Continue reading “Mini” CRISPR tool reworks inactive protein for better gene editing

CRISPR therapy for rare blood disease delivers “life-changing” results

New data from the United States’ first CRISPR gene editing clinical trial indicates the treatment is safe and effective more than two years after initial dosing. Targeting a pair of rare genetic blood diseases, the experimental therapy has so far been … Continue reading CRISPR therapy for rare blood disease delivers “life-changing” results

World-first CRISPR-edited sugarcane helps reduce environmental impact

Sugarcane is an important food crop, but it’s large environmental impact means there’s plenty of room for improvement. Unfortunately it’s tricky and time-consuming to breed new varieties, but now researchers have used CRISPR gene-editing to do so quick… Continue reading World-first CRISPR-edited sugarcane helps reduce environmental impact