Alzheimer’s Disease – Page 21

New insights into how COVID-19 can impact the brain and CNS

Posted on January 13, 2021 by Rich Haridy

New research demonstrates SARS-CoV-2 can directly infect brain cells

A robust new study led by scientists from Yale School of Medicine has comprehensively demonstrated how SARS-CoV-2, the novel coronavirus that causes COVID-19, can infect the brain and central nervous system (CNS). The study validates a growing body of observational research attributing neurological issues to COVID-19.

Category: Health & Wellbeing, Lifestyle

Tags: Coronavirus (COVID-19), Virus, Brain, Neuroscience, Yale, Dementia, Alzheimer’s Disease, Parkinson’s Disease, Neurological, New Atlas Audio

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Alzheimer’s brain tissue study uncovers three distinct disease subtypes

Posted on January 8, 2021 by Rich Haridy

Researchers analyzed more than 1,500 postmortem brain tissue samples to distinguish the molecular differences between various cases of Alzheimer's disease

Despite decades of rigorous research, scientists are still struggling to crack the mystery of Alzheimer’s disease. Promising preclinical research has consistently led to frustrating clinical trial failures and some have started to question whether we are even targeting the correct pathological mechanisms.

Category: Science

Tags: Alzheimer’s Disease, Dementia, Neuroscience, Brain, Molecules, Mount Sinai Hospital, New Atlas Audio

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White blood cell mutation may drive early stages of dementia

Posted on December 23, 2020 by Rich Haridy

Novel findings point to new research pathways to treat neurodegenerative disease such as Alzheimer's

Research into an ultra-rare type of early-onset dementia has uncovered a novel genetic mutation that results in dysfunctional white blood cells and a breakdown of the blood-brain barrier. The study suggests this newly discovered mechanism of neurodegeneration may play a role in more common types of dementia, such as Alzheimer’s disease.

Category: Science

Tags: Brain, Blood-brain barrier, Blood, Dementia, Neuroscience, Alzheimer’s Disease, Trinity College Dublin, New Atlas Audio

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Google-Glass-like smell stimulation device proposed as dementia therapy

Posted on December 23, 2020 by Rich Haridy

It's hoped a prototype wearable device will allow clinical trials to test whether olfactory stimulation can help treat neurodegenerative disease

A novel wearable device has been proposed to deliver electrical pulses stimulating the olfactory system as a way of preventing or slowing dementia-related neurodegeneration. A dysfunctional sense of smell is suspected to be one of the earliest signs of Alzheimer’s and Parkinson’s so it is hypothesized these diseases could be prevented by olfactory stimulation.

Category: Medical, Science

Tags: Alzheimer’s Disease, Parkinson’s Disease, Dementia, Wearable, Brain stimulation, Neuroscience, Smell, University of Otago

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Biomarker of Alzheimer’s found to be regulated by sleep cycles

Posted on December 17, 2020 by Nick Lavars

Immune cells known as microglia (turquoise with red dots) surrounding amyloid plaques

Scientists at Washington University School of Medicine (WUSM) in St. Louis have spent some years investigating the links between circadian rhythm and Alzheimer’s, and have recently been making some real inroads. Following a 2018 study demonstrating how disrupted sleep can accelerate the buildup of toxic plaques associated with the disease, the team has now identified a protein implicated in the progression of the disease that appears highly regulated by the circadian rhythm, helping them join the dots and providing a potential new therapeutic target.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Circadian Rhythms, Sleep, Washington University School of Medicine

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New technique tracks a culprit of Alzheimer’s in spinal fluid

Posted on December 9, 2020 by Nick Lavars

A heat map of the brain showing where tau proteins are concentrated

In their efforts to pick up the disease as early as possible, scientists are searching far and wide through the human body for tell tale signs of Alzheimer’s. A team from the Washington University School of Medicine in St. Louis has come up with a technique it says can detect one of these biomarkers in cerebrospinal fluid, which could lead to earlier diagnoses and more effective treatments.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Washington University in St Louis

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Blood test predicts risk of mild memory loss developing into Alzheimer’s

Posted on December 1, 2020 by Nick Lavars

Blood tests are emerging as an exciting tool for the detection of Alzheimer's disease in its early stages

Blood tests are starting to show real potential as a way of detecting Alzheimer’s disease in its early stages, with a number of studies producing highly promising results in the past couple of years. Joining them is a new test that can analyze markers in the blood of those with mild memory loss to determine the risk of them going on to develop Alzheimer’s within two to four years.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Blood, Lund University, New Atlas Audio

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Anxiety independently linked to faster onset of Alzheimer’s disease

Posted on November 27, 2020 by New Atlas - New Technology & Science News

Research has found a link between anxiety and an increased rate of progression from mild cognitive impairment to Alzheimer's

Feelings of apprehension and fear are often observed in those suffering mild cognitive impairment (MCI), and previous research has suggested that anxiety could be an early indicator for Alzheimer’s disease, which often follows MCI. Now a new study has found an association between anxiety and an increased rate of progression from MCI to Alzheimer’s disease.

Category: Medical, Science

Tags: Alzheimer’s Disease, Medical University of South Carolina, Neurological, Anxiety

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Study offers “indisputable” link between Alzheimer’s and gut microbiome

Posted on November 16, 2020 by Nick Lavars

A new study has highlighted the role gut bacteria may play in Alzheimer's disease, while inflammation may also have a part to play

Research into the relationship between the brain and the bacteria in our bellies is uncovering links to an increasing number of neurological conditions, with Alzheimer’s among them. A new study is throwing further weight behind the theory that an imbalance in the gut microbiome may be related to the onset of the disease, showing how shifts in bacterial diversity are associated with inflammation and heightened numbers of amyloid plaques in the brain, one of the hallmarks of the condition.

Category: Medical, Science

Tags: Alzheimer’s Disease, Microbiome, Gut Bacteria, Dementia, University of Geneva, New Atlas Audio

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Experimental ALS drug prolongs survival in Phase 2 human trial

Posted on October 19, 2020 by Rich Haridy

The ALS Association is petitioning the FDA to forego Phase 3 trial requirements so the new drug can be put on the market immediately

An experimental drug treating amyotrophic lateral sclerosis (ALS) is demonstrating promising potential, both slowing the progression of this neurodegenerative disease and prolonging patient survival. Phase 2 human trials are complete and Amylyx Pharmaceuticals, the company developing the treatment, says it is working with regulatory bodies on the steps necessary to bring the drug to market ahead of a Phase 3 trial.

Category: Health & Wellbeing, Lifestyle

Tags: Drugs, FDA, Massachusetts General Hospital, Neuroscience, Neurological, Alzheimer’s Disease, New Atlas Audio

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