Alzheimer’s Disease – Page 18

Difficulty hearing speech in noisy rooms may be early sign of dementia

Posted on July 22, 2021 by Rich Haridy

Experts are divided over whether treating

An impressively large study following more than 80,000 people for 11 years has found that difficulty hearing speech in noisy environments can be an early-warning sign of later-life dementia. The next steps for the research will be to investigate whether immediately treating mid-life hearing impairments can reduce the risk of dementia developing in a person’s senior years.

Category: Health & Wellbeing, Lifestyle

Tags: Hearing, Hearing Impaired, Dementia, Alzheimer’s Disease, Aging, University of Oxford, New Atlas Audio

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Metal, microbubbles and ultrasound combine to fight Alzheimer’s plaques

Posted on July 15, 2021 by Nick Lavars

Brain imaging shows the accumulation of a metal-based molecule in the region of the brain targeted with ultrasound

Among the more interesting ways scientists hope to tackle the roots of Alzheimer’s disease is by using microbubbles to prise open the blood brain barrier and sneak in drugs that bust apart toxic plaques. A team in the UK has found new success using this experimental approach, demonstrating how the technique can be combined with ultrasound and a novel metal-based molecule to prevent this type of plaque buildup in its early stages.

Category: Medical, Science

Tags: Alzheimer’s Disease, Blood-brain barrier, Imperial College, Dementia, New Atlas Audio

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Metal, microbubbles and ultrasound combine to fight Alzheimer’s plaques

Posted on July 15, 2021 by Nick Lavars

Brain imaging shows the accumulation of a metal-based molecule in the region of the brain targeted with ultrasound

Category: Medical, Science

Tags: Alzheimer’s Disease, Blood-brain barrier, Imperial College, Dementia, New Atlas Audio

Continue reading Metal, microbubbles and ultrasound combine to fight Alzheimer’s plaques→

Dementia-fighting experimental drug moves to human trials

Posted on June 30, 2021 by Rich Haridy

A new drug called SAK3 has shown promising preclinical results in animal models of Alzheimer's and Lewy Body dementia

After years of preclinical work, Japanese researchers have announced a new kind of drug treatment for dementia and Alzheimer’s disease is ready to move to human clinical trials. A number of animal studies have shown the novel drug to improve cognition and reduce signs of neurodegeneration in a number of dementia-causing diseases.

Category: Health & Wellbeing, Lifestyle

Tags: Neuroscience, Dementia, Alzheimer’s Disease, Parkinson’s Disease, Brain, Tohoku University, New Atlas Audio

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Ultrasound boosts memory of aging mice in Alzheimer’s study

Posted on June 23, 2021 by Nick Lavars

Ultrasound may be a way to not just tackle brain plaques associated with Alzheimer's, but also age-related cognitive decline in the broader population

One promising possibility when it comes to treating Alzheimer’s is the idea of using non-invasive ultrasound to take out toxic brain plaques, and a group of researchers in Australia have been at the cutting edge of this technology for a number of years. The scientists’ latest investigations have uncovered some surprising new ways this technique can improve cognition in mouse models of the disease, which they believe could have wider implications for restoring cognition in the elderly.

Category: Medical, Science

Tags: Alzheimer’s Disease, University of Queensland, Memory, Aging, Ultrasound, New Atlas Audio

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FDA Alzheimer’s call slammed as “Worst drug approval in recent US history”

Posted on June 18, 2021 by Rich Haridy

The recent FDA approval for a new Alzheimer's drug raises questions over what factors the regulatory body should take into account when authorizing new medicines

The US Food and Drug Administration’s controversial recent approval of Alzheimer’s drug Aduhelm has been subject to vociferous criticism from many in the scientific community. Amidst concerns surrounding the drug’s efficacy and price, several expert advisors to the FDA have resigned in protest and calls for top officials to step down are growing.

Category: Science

Tags: FDA, Alzheimer’s Disease, Drugs

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First brain observations of faulty memory sheds light on Alzheimer’s

Posted on June 9, 2021 by Nick Lavars

Scientists have used experiments on rats to identify specific patterns of brain cell activity that can relate to correct and incorrect memories

Through a new study on rodents, scientists have made first-of-a-kind observations of the brain mistakenly recalling a memory. The researchers were able to identify patterns of brain cell activation as mistakes were made during memory experiments, which the scientists believe lays the groundwork for understanding the mechanisms at play in memory disorders such as Alzheimer’s disease.

Category: Medical, Science

Tags: Alzheimer’s Disease, University of Texas, Brain, Memory, New Atlas Audio

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Blood biomarker detects whether depression is due to neurodegeneration

Posted on June 8, 2021 by Rich Haridy

A test could be used as a rapid screening tool in clinics to determine whether a patient's cognitive problems are due to neurodegeneration.

A new study published in the journal Nature Communications is reporting a single blood-based biomarker can detect the presence of 13 neurodegenerative disorders, from frontotemporal dementia to motor neuron disease. The test cannot specifically distinguish each disorder but instead is proposed as a way to determine whether patients with memory problems are suffering from the early stages of neurodegenerative disease.

Category: Medical, Science

Tags: Brain, Alzheimer’s Disease, Parkinson’s Disease, Dementia, Blood, Diagnosis, King’s College London, New Atlas Audio

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First new Alzheimer’s drug in decades receives controversial FDA approval

Posted on June 8, 2021 by Rich Haridy

Approval of a new Alzheimer's drug comes after a FDA advisory panel last year overwhelmingly concluded there is not enough evidence to claim it is effective

A new Alzheimer’s disease treatment has been controversially approved for use in the United States despite an independent Food and Drug Administration (FDA) advisory panel reporting last year the drug’s Phase 3 trial results were inconclusive. The approval marks the first new treatment for Alzheimer’s in almost 20 years.

Category: Health & Wellbeing, Lifestyle

Tags: Alzheimer’s Disease, Dementia, FDA, Brain, New Atlas Audio

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Massive blood sampling study identifies predictors of Alzheimer’s risk

Posted on May 19, 2021 by Nick Lavars

Scientists have identified a new set of blood-based biomarkers that may help predict Alzheimer's risk

While the exact causes behind Alzheimer’s are still unknown, research is beginning to demonstrate how biomarkers of the disease might reveal themselves long before symptoms appear, raising the prospect of earlier diagnosis and better treatments for patients. A new study, claimed to be the most comprehensive of its type, has demonstrated how concentrations of certain proteins in the blood might indicate the onset of the condition far in advance, and has pinpointed one that may even help trigger it.

Category: Medical, Science

Tags: Alzheimer’s Disease, Dementia, Blood, Johns Hopkins University, New Atlas Audio

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