Supercharged cellular cleaning process prevents clogged arteries in mice

Researchers at the Albert Einstein College of Medicine have discovered a new potential way to prevent arteries clogging, and as such reduce the risk of heart attacks and strokes. The technique involves ramping up a cleaning process that naturally slows… Continue reading Supercharged cellular cleaning process prevents clogged arteries in mice

Novel drug rejuvenates cellular cleaning to reverse Alzheimer’s in mice

An artist's impression of tau tangles taking hold in the brain, which are considered one of the drivers of Alzheimer's disease

A key focus for medical scientists working to prevent or potentially treat Alzheimer’s is coming up with ways to avoid the buildup of toxic proteins in the brain, which could include the use of ultrasound or maybe even regular deep sleep. A team at the Albert Einstein College of Medicine has uncovered another promising pathway, discovering that an experimental drug can supercharge a natural cellular cleaning mechanism to rid mice of these unwanted waste products, and reverse key symptoms of the disease.

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Questions raised over efficacy of cutting-edge new migraine drugs

Last year erenumbab was approved by the FDA, the first in an entirely new class of drugs designed to help migraine sufferers to reach the general public. A study is now reporting successful Phase 3 clinical trial results for a new orally admi… Continue reading Questions raised over efficacy of cutting-edge new migraine drugs

Scientists complete first map of an animal's nervous system in "major milestone"

Scientists have mapped the entire nervous system of a roundworm called C. elegans

The brain is by far our most complex organ, with its billions upon billions of neurons that talk to each other through a vast network of synaptic connections. But there are simpler ways we can improve our understanding of it than mapping this impossibly intricate web. Enter a millimeter-long roundworm known as Caenorhabditis elegans, which scientists have been using as a model to study the human brain for some time, but have now compiled what they call the first complete map of its entire nervous system.

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