Collaborate Disseminate
It’s estimated that 27.5% of people globally are affected by pain. While they might be effective, existing analgesics each have their issues. Acetaminophen/paracetamol (Tylenol, Panadol) can be toxic to the liver, and non-steroidal anti-inflammatory dr… Continue reading New non-toxic analgesic provides hope to nerve pain sufferers
With the world in an opioid crisis, the development of non-opioid analgesics has become more urgent. A series of Phase 3 clinical trials into a novel oral, non-opioid painkiller has found that it’s effective in treating acute pain in both surgical and … Continue reading Non-opioid proves effective for acute surgical & non-surgical pain
Most of us have woken up with an aching back after a night of tossing and turning, only for that pain to then keep us awake the next night. Now, Harvard scientists have discovered a potential link between pain and poor sleep, and maybe even a way to br… Continue reading Harvard scientists identify link between pain and poor sleep
Most of us have woken up with an aching back after a night of tossing and turning, only for that pain to then keep us awake the next night. Now, Harvard scientists have discovered a potential link between pain and poor sleep, and maybe even a way to br… Continue reading Harvard scientists identify link between pain and poor sleep
After screening 27 million compounds, researchers have found a small-molecule drug that performed as well as a common painkiller with no side effects in rodent tests. The hope is that the finding could lead to better pain management for humans.Continue… Continue reading New compound knocks out 4 types of pain with no side effects in study
Paracetamol and ibuprofen are among the world’s most common over-the-counter painkillers, but manufacturing them requires crude oil. Now, researchers at the University of Bath have developed a more sustainable method, creating the drugs out of waste pr… Continue reading Painkiller producers could pivot to paper waste instead of crude oil
A few years ago, Scottish woman Jo Cameron was found to be a medical marvel who felt next to no pain, fear or anxiety, and had faster wound healing, thanks to a specific gene mutation. Now, scientists have studied in more detail to figure out how this … Continue reading Genetic study reveals why Scottish woman feels no pain, heals faster
Early preclinical work led by researchers from Harvard Medical School has found certain elements in a toxin produced by the anthrax bacterium can silence activity in pain-signaling brain neurons. The research proposes this could be a new model for futu… Continue reading Anthrax toxin may be the key to new pain-blocking therapies
A newly published consensus statement, co-signed by nearly 100 scientists, is calling for the common painkiller acetaminophen (also known as paracetamol or APAP) to be used cautiously and conservatively during pregnancy. The researchers indicate there … Continue reading Scientists call for limited use of acetaminophen during pregnancy
An intriguing new proof-of-concept study from a team of University of California San Diego researchers suggests CRISPR gene therapy may be a promising alternative to opioids for chronic pain. The preliminary investigation demonstrated lowered pain sens… Continue reading Unique CRISPR gene therapy offers opioid-free chronic pain treatment