Repurposed blood cancer drug could remove need for lifelong HIV meds

A new study has repurposed an existing blood cancer drug, using it to eliminate dormant HIV-infected cells that can cause the infection to reactivate when suppressive antiretroviral treatment is interrupted. The drug could change the lives of people wi… Continue reading Repurposed blood cancer drug could remove need for lifelong HIV meds

German man third to be completely cured of HIV after stem cell transplant

A 53-year-old from Düsseldorf in Germany has become the third person in the world to be completely cured of HIV following a stem cell transplant using donor cells with a particular genetic mutation.Continue ReadingCategory: Medical, ScienceTags: HIV an… Continue reading German man third to be completely cured of HIV after stem cell transplant

Major setback as another large ongoing Phase 3 HIV vaccine trial fails

In a blow to researchers all across the world, the only HIV vaccine currently in Phase 3 human trials has been deemed a failure and studies have been discontinued. The experimental vaccine was being tested in thousands of participants across Europe, No… Continue reading Major setback as another large ongoing Phase 3 HIV vaccine trial fails

Refined “kick and kill” strategy eliminates HIV in infected mice

HIV is tricky to eliminate thanks to its tendency to hide out in cellular reservoirs, but a growing body of work shows that a cure might be possible. In a new study, improvements to a previous “kick and kill” technique were able to completely clear out… Continue reading Refined “kick and kill” strategy eliminates HIV in infected mice

Drugs that trip cellular alarm could help clear out hibernating HIV

HIV can currently be managed with a lifelong daily drug regimen, but unfortunately the infection can’t be eliminated entirely. Now, researchers have found a potential way to trip a cellular “alarm” to alert the immune system to clear out infected cells… Continue reading Drugs that trip cellular alarm could help clear out hibernating HIV

Cancer immunotherapy hunts down hidden HIV in mouse study

HIV is an insidious virus, able to hibernate inside infected cells ready to re-emerge if treatment is stopped. Now, a team of researchers has found a way to shrink that viral reservoir by adapting a cancer immunotherapy technique to supercharge immune … Continue reading Cancer immunotherapy hunts down hidden HIV in mouse study

Bi-monthly injection prevents HIV infection, early trial data suggests

A large-scale phase 2b/3 trial testing the efficacy of a novel drug designed to prevent HIV infection has been cut short due to a combination of positive early data and disruptions caused by the COVID-19 pandemic. The interim analysis of the drug sugge… Continue reading Bi-monthly injection prevents HIV infection, early trial data suggests

Immune cells reprogrammed to kill HIV-infected T cells

Researchers have reprogrammed cells to give them the ability to fight HIV infection like so-called "HIV ...

There exists a group of HIV-positive people who have the rare ability to naturally control the HIV infection. Now, after years of research, a team of scientists from the Institut Pasteur in Paris, has successfully reprogrammed cells that lack this ability, giving them the same incredible, antiviral potency.

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Scientists combine CRISPR and drug therapy to cure HIV infection in mice for the first time

Though advances in medicine have greatly improved the lives of HIV sufferers and made the virus much more manageable, a permanent cure has remained elusive. Scientists have now made a significant breakthrough in this area, using the CRISPR-Ca… Continue reading Scientists combine CRISPR and drug therapy to cure HIV infection in mice for the first time