World-first drug lowers genetic form of “bad cholesterol” by up to 65%

A groundbreaking oral drug has been developed that lowers lipoprotein(a), a previously untreatable largely inherited form of 'bad cholesterol'

Researchers have developed the world’s first oral drug to target a form of cholesterol that has previously been untreatable and is largely caused by genetics, making it difficult to control by way of exercise, diet or other lifestyle factors.

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New pill targets “undruggable” protein to selectively kill cancer cells

Researchers have developed a drug that targets a protein essential for the growth and survival of cancer cells. The pill was found to be effective in preclinical studies and is now the subject of human clinical trials.Continue ReadingCategory: Medical,… Continue reading New pill targets “undruggable” protein to selectively kill cancer cells

“Molecular wedge” renders superbugs vulnerable to antibiotics again

We’re locked in an arms race with bacteria – and worryingly, it looks like we’re losing, as they increasingly develop resistance to our best drugs. Now, scientists at the University of Oklahoma have identified a new class of molecules that disable a ma… Continue reading “Molecular wedge” renders superbugs vulnerable to antibiotics again

Painkiller producers could pivot to paper waste instead of crude oil

Paracetamol and ibuprofen are among the world’s most common over-the-counter painkillers, but manufacturing them requires crude oil. Now, researchers at the University of Bath have developed a more sustainable method, creating the drugs out of waste pr… Continue reading Painkiller producers could pivot to paper waste instead of crude oil

New molecule chops up RNA of “undruggable” common cancer-causing gene

A gene called MYC is implicated in the majority of cancers, but unfortunately it’s often considered “undruggable.” In a new study scientists have developed a molecule that chops up the RNA of this gene, effectively clearing cancer in mice.Continue Read… Continue reading New molecule chops up RNA of “undruggable” common cancer-causing gene

Trial drug shown to significantly slow early Alzheimer’s decline

The drug donanemab, which destroys the amyloid beta plaques that cause Alzheimer's disease, was the subject of a Phase 3 clinical trial

A Phase 3 clinical trial of the drug donanemab has shown it can significantly slow cognitive and functional decline in people with early-stage Alzheimer’s disease, compared with existing treatments.

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Breath of life: A simple inhaler could cut postpartum hemorrhage deaths

Melbourne’s Monash University has commenced a Phase 1 clinical trial to test a novel inhaled powder designed to prevent postpartum hemorrhage, a serious complication of childbirth that causes tens of thousands of deaths worldwide.Continue ReadingCatego… Continue reading Breath of life: A simple inhaler could cut postpartum hemorrhage deaths

Advanced microparticles may make missed meds a thing of the past

Taking prescription medications in the right dose at the right time can directly impact a patient’s health. Conversely, missing medications or not taking them as required can have costly results. Bioengineers at Rice University may have the solution to… Continue reading Advanced microparticles may make missed meds a thing of the past